Evaluation Of The Efficacy And Safety Of Carbetocin In Preventing Postpartum Hemorrhage During Cesarean Section With Hypertension During Pregnancy

Objective To investigate the efficacy and safety of cabernet in preventing postpartum hemorrhage in patients with hypertensive disorder complicating pregnancy.Methods A total of 100 cases of gestational hypertension cesarean section were selected as the research subjects,according to the random digital table method,were divided into control group(n=50)and observation group(n=50).Patients in the control group were given oxytocin treatment,patients in observation group were treated with carbetocin combined with oxytocin.Blood loss of 2 h and 24 h postpartum hemorrhage,the case number of postpartum hemorrhage,the weight of the newborn,the neonatal asphyxia and the adverse drug reaction rate,postpartum 24 h Hb decline,third stage of labor and amniotic fluid characteristics were compared.Results The blood loss of 2 h,24 h postpartum hemorrhage,the number of postpartum hemorrhage of the observation group were significantly lower than those in the control group(P<0.05).The decrease of 24 h Hb in the observation group was significantly lower than that in the control group,and the duration of labor in the third group was significantly shorter than that in the control group(P<0.05),and there were no significant difference in 1 min Apgar score,the weight of the newborn,and amniotic fluid(P>0.05).The adverse drug reaction rate in observation group was significantly lower than that in the control group(P<0.05).Conclusions Carbetocin induced hypertension during pregnancy can effectively reduce postpartum hemorrhage of cesarean section,has high safety,and certain clinical value.