Clinical Observation Of Jiawei Chengshi Juanbi Decoction Formula Granule In The Treatment Of Nerve Root Type Cervical Spondylopathy (wind-cold-dampness Syndrome)

Objective: To observe the clinical effect and side effects of modified Cheng’s Juanbi Decoction in the treatment of cervical spondylotic radiculopa(CSR)by scientific grouping,so as to provide clinical reference for the treatment of cervical spondylotic radiculopathy by traditional Chinese medicine.Methods: from March 2019 to January 2020,60 cases of CSR were selected from the orthopedic department of the Second Affiliated Hospital of Hunan University of traditional Chinese medicine.According to the method of random number table,30 cases in the treatment group and 30 cases in the control group were divided into two groups.The treatment group was treated with modified chengshijuanbi Decoction formula granules,and the control group was treated with Gentongping granules.The visual analogue of pain before and after treatment was compared between the two groups Score(VAS)score,cervical spondylotic radiculopathy 20 score(Yasukuni Tanaka)score,the total effective rate of clinical efficacy,the two groups of patients were evaluated,and the drug safety and side effects were observed.Result:1.After treatment,the two groups of blood pressure,pulse,body temperature,respiration,three major routine,liver,kidney function,electrolyte and electrocardiogram and other safety indicators were not significantly changed compared with before treatment.The two groups of treatment methods are safe and reliable for human body without obvious toxic side effects.2.There was significant difference in VAS score and clinical symptom score between the two groups before and after treatment(P<0.05).Comparison of the total effective rate of the two groups after treatment: the total effective rate of the treatment group :80%,the control group :57%,the was statistically significant(P<0.05),and the curative effect of thetreatment group was better than that of the control group.Conclusion: the modified formula granules of Cheng’s Juanbi decoction have better clinical effect on CSR(wind cold and dampness syndrome),less toxic and side effects,and are worth popularizing.