Clinical Observation On The Treatment Of Primary Dysmenorrhea Of Cold Coagulation And Blood Stasis Type With Wuyu Nuangongtie And Shaofu Zhuyu Decoction

Objective: the purpose of this study is to explore the clinical effect of wuyunuangong plaster therapy combined with Shaofu Zhuyu Decoction in the treatment of primary dysmenorrhea of cold coagulation and blood stasis type,and to provide effective methods and ideas for the treatment.Methods: 60 patients with primary dysmenorrhea of cold coagulation stasis type were selected from the gynecological clinic of Shanxi Hospital of traditional Chinese medicine from January 2019 to December 2019.According to the order of treatment,the patients were divided into two groups: the experimental group and the control group.The control group was treated with Shaofu Zhuyu Decoction,and the experimental group was treated with Wuyu Nuangong plaster on Shenque point on the basis of the control group.All patients began to take medicine 3 days before menstruation,and stopped taking medicine after menstruation was clean.Three menstrual cycles were a course of treatment.The pain degree of dysmenorrhea,menstrual volume,color,quality and menstruation accompanying symptoms,TCM syndrome score,TCM symptom score,dysmenorrhea intensity score and changes of individual symptoms of each syndrome were observed before and after treatment.To evaluate the clinical effect of Shaofu Zhuyu Decoction Combined with Wuyu Nuangongtie in the treatment of primary dysmenorrhea.Result:1.60 patients were enrolled in this study.There was no significant difference between the two groups in age,course of disease and condition before treatment(P > 0.05).There was no significant difference in TCM syndrome score,symptom score and pain intensity(VAS score)between the two groups before treatment(P > 0.05).There was no significant difference between the two groups before treatment(P > 0.05),indicating that the two groups were balanced and comparable.2.There was no significant difference in TCM symptom score,dysmenorrhea intensity(VAS score)and TCM syndrome score between the two groups(P.After treatment,the scores of TCM symptoms,syndromes and vas in the experimental group were significantly lower than those in the control group.After independent sample t test,the difference was statistically significant(P < 0.05),suggesting that the effect of improving TCM symptoms,syndromes and vas in the experimental group was significantly better than that in the control group.3.Comparison of the effective rate of the two groups: in TCM symptoms,the experimental group: 6 cases cured,17 cases effective,6 cases effective,1 case ineffective,the effective rate accounted for 96.6%;the control group: 2 cases cured,15 cases effective,8 cases effective,5 cases ineffective,the effective rate accounted for 83.3%.In the aspect of TCM syndromes,the experimental group: cured 3 cases,effective 11 cases,effective 14 cases,ineffective 2 cases,effective rate accounted for 93.3%;the control group: cured 0cases,effective 8 cases,effective 16 cases,ineffective 6 cases,effective rate accounted for80%.4.Before and after treatment,the scores of each single symptom in the two groups were paired t-test,P < 0.05,the difference was statistically significant.It was pointed out that after treatment,each single symptom in the two groups was significantly relieved compared with that before treatment.After treatment,the scores of each single symptom in the two groups were p > 0.05 by independent sample t-test,except for nausea and vomiting and cold sweat dripping,the difference was not statistically significant,indicating that the two single symptoms were nausea and vomiting and cold sweat dripping The efficacy of the test group was similar to that of the control group,and the scores of other single symptoms were lower than that of the control group(P < 0.05).5.Correlation factors: there was no significant difference between the therapeutic effect of TCM syndromes and their age,course of disease and degree of illness in the experimental group(P > 0.05),indicating that the therapeutic effect of TCM syndromes had nothing to do with them.6.Safety observation: the two groups of drugs used in the treatment process and after the treatment are in the safe range,and no obvious adverse reactions and side effects(skin allergy,skin pruritus,rash,blister,dizziness,nausea,etc.)are found in the clinical observation.Before and after the treatment,the patient’s body temperature,pulse,breath,blood pressure,blood routine,urine routine,liver function and kidney function are not obvious Abnormal.Conclusion:1.The clinical effect of Wuyu warm palace paste combined with Shaofu Zhuyu Decoction in the treatment of primary dysmenorrhea of cold coagulation and stasis type is significant,which is superior to Shaofu Zhuyu Decoction.2.Wuyu warm palace paste combined with Shaofu Zhuyu decoction is better than Shaofu Zhuyu Decoction in TCM symptoms,TCM syndromes and VAS scores.It is more effective than the experimental group in improving menstrual cold pain,chilly limbs,less or not smooth menstrual blood volume,dark block of menstrual color,loose stools,waist trouble and anal drop.3.Wuyu warm palace paste Shenque point paste take,long-term curative effect is good,safety is high,it is worth clinical application.