A Clinical Observation On Children’s Acute Bronchitis Treating With Mongolian Medicinal Preparation Tuximul-3 Pill

Objective : Through a control observation on a clinical treatment of combining Mongolian medicine with Western medicine,the clinical efficacy and safety of Mongolian medicinal Tuximul-3 pill for acute bronchitis in children(ABC)will be evaluated scientifically,and the differences of total effective rate(TER)between Tuximul-3 pill and Azithromycin tablet will be figured out preliminarily,as well as a clinical suggestion for the first-choice Mongolian medicine prescription to treat this disease will be proposed via this result of the study.Method : With the informed consent of the relevant parents,60 children confirmed with ABC who met the inclusion criteria were selected to participate in this clinical study voluntarily.These diseased children were randomly divided into Mongolian medicine treatment group(MMt group)and Western medicine control group(WMc group),30 cases were treated with Tuximul-3 pills orally in MMt group,while 30 cases were treated with Azithromycin dispersible tablets orally in WMc group.Statistical t test and analysis of variance were applied to compare and analyze the differences between the two groups referring to the clinical major symptoms and minor symptoms of ABC and its laboratory data.All the patients in both groups in the study were treated for 7 days.Result : TER of post-treatment was compared between the two groups: TER was respectively 90.00% in MMt group and 83.33%in WMc group according to statistical analysis,there was no significant difference between the two groups(P>0.05);TER of clinical symptom improvement after treatment was compared between the two groups: TER was respectively 93.33% in MMt group and 70.00% in WMc group,there was a significantly difference exist between the two groups(P ? 0.05),and MMt group’s effectiveness was obviously superior to WMc group’s;Comparison of the post-treatment scores of the clinical major symptoms improvement between the two groups: The improvement of cough duration(day and night)and cough frequency per minute and duration of each cough in MMt group were significantly better than that of those major symptoms in WMc group(P < 0.05).There was no significant difference in the improvement of fever between the two groups’ patients(P>0.05);Comparison of the post-treatment scores of the clinical minor symptoms improvement between the two groups: the improvement of dry mouth,appetite,constipation,nausea and other symptoms in MMt group was significantly better than that of those minor symptoms in WMc group(P < 0.05),and there was no significant difference in improvement of symptoms such as complexion,pharyngeal congestion,sleep disorder and other symptoms between the two groups(P > 0.05);Comparison of the laboratory test results between the two groups: there were no significant differences between the post-treatment data about WBC,NEUT%,CRP in the two groups(P>0.05).Conclusion : Mongolian medicine Tuximul-3 pill can effectively improve the major and minor symptoms of ABC,and it has the suppressive effect of controlling the inflammatory response of ABC.Meanwhile,its clinical therapeutic effect on ABC is almost the same as the effect of Azithromycin to treat the disease,which verifiesthat the pill has the high value of application in pediatric clinical practise.