Analysis Of Nosocomial Infection Index In A Neonatal Intensive Care Unit In A Tertiary Hospital In Suzhou

Objective:To investigate the status of nosocomial infection in Neonatal Intensive Care Unit(NICU)of a tertiary hospital in Jiangsu Province,and to analyze the characteristics and high risk factors of NICU nosocomial infection,so as to provide scientific basis for formulating prevention and control measures of NICU nosocomial infection and reducing nosocomial infection rate.Method:Objective surveillance method was used to monitor all NICU newborns admitted to a tertiary hospital in Jiangsu Province from January 2015 to December 2017.A special surveillance form was designed to collect case data actively.The data were analyzed by F test and Chi square test.Result:During the three years,4503 NICU neonates were monitored,199 cases(216 times)of nosocomial infection occurred,the infection rate was 4.42%,the infection rate was 4.80%;the total hospitalization days of neonates were 43006 days,the infection rate was 4.63,the infection rate was 5.02,and the infection rate of neonates whose birth weight was less than 1000g was the highest(29.45%).The neonatal catheter usage rate was 32.87%,the incidence of catheter-related bloodstream infection was 0.92 in NICU.The highest incidence of catheter usage rate and catheter-related bloodstream infection was found in the group with birth weight less than 1000g(60.30%,3.81).The neonatal ventilator use rate of NICU was 12.40%,the incidence of ventilator-associated pneumonia was 3.19 and the highest incidence of ventilator use rate and catheter-related bloodstream infection was<1000g at birth(39.03%,6.54).The nosocomial infection site was mainly defeated/bacteremia(66.67%),followed by the lower respiratory tract(20.83%).Klebsiella pneumoniae was the main pathogen of nosocomial infection(24.30%),followed by coagulase negative Staphylococcus(16.82%).The results showed that the incidence of NICU nosocomial infection was significantly correlated with birth weight,gestational age,Apgar 1 minute score,severe preeclampsia,neonatal asphyxia,intravenous nutrition,mechanical ventilation,umbilical vein intubation,PICC intubation,antibiotics use>7 days,hospital stay>14 days,and maternal age,delivery There was no significant correlation between the way,placenta deformity,amniotic fluid pollution and maternal fever.Logistic regression analysis showed that birth weight(<1500g),gestational age(<32 weeks),Apgar score(<7 points),severe preeclampsia,intravenous nutrition,mechanical ventilation,umbilical vein intubation,PICC intubation were independent risk factors of NICU neonatal hospital infection.Conclusion:The incidence of NICU nosocomial infection is related to many factors.We should pay more attention to the newborns with low birth weight,small gestational age,low Apgar 1-minute score,severe preeclampsia and neonatal asphyxia.At the same time,we should be careful to use invasive operation,rational use of antibiotics and shorten hospital stay to reduce the incidence of nosocomial infection.Life.At the same time,further standardize the management of hospital infection,carry out targeted surveillance of neonatal hospital infection,pay attention to the standardization of prevention and control measures,can effectively reduce the incidence of hospital infection.