The Efficacy Of Anti-vegf In Treating Macular Edema Caused By Branch Retinal Vein Occlusion With Qi Stagnation And Blood Stasis Was Retrospectively Analyzed

AIM:By observing and analyzing the best corrected visual acuity and retinal thickness at the center of macular edema before and after anti-vegf treatment for branch retinal vein occlusion with Qi stagnation and blood stasis type,To evaluate the effect of anti-vegf on branch retinal vein occlusion(BRVO)macular edema.Methods:Retrospective case before and after treatment of self-reflection.Patients diagnosed with branched retinal vein occlusion secondary to macular edema who visited the affiliated hospital of chengdu university of traditional Chinese medicine from March 2017 to March 2018 were collected.The subjects of this study were 30 patients with branch retinal vein occlusion of qi-stagnation and blood-stasis type who had received anti-vegf treatment,and general data(gender,age,course of disease,baseline vision,baseline CMT,and injection times)were recorded.Follow-up was conducted in the third,sixth and December.Record patients’ best corrected visual acuity(BCVA),macular central retinal thickness(CMT),data using SPSS25.0 statistical software for statistical analysis,center for vision and macular retinal thickness by Spearman correlation,factors affecting the long-term vision using multiple regression analysis,the best corrected visual acuity between the three groups using will kirk’s symbol rank test were compared,with P < 0.05 for the difference was statistically significant.Result:1.30 patients with BRVO complicated with macular edema,aged 35-66 years,with an average age of 47.92 ±10.026 years.There were 12 males and 18 females.After statistical analysis,the age and sex of the three groups were balanced.2.The mean of the third,sixth and twelfth visual acuity were 36.1± 20.891,39.63 ±16.591,41.1± 16.896,mean BCVA was 41.33± 16.75,and the difference was statistically significant(P<0.05).3.Correlation analysis of long-term BCVA and all variables: the results showed that there was a positive correlation between baseline vision and long-term BCVA,with the correlation coefficient = 0.913,P<0.05,and the difference has statistically significant.4.Multiple regression analysis of factors affecting long-term BCVA: It has no correlation between injection times,age,baseline CMT,baseline vision and long-term BCVA,and the differences were not statistically significant.Gender was positively correlated with long-term BCVA,and women had better long-term vision.5.Baseline CMT was 346 ±64.134,and The mean value of CMT in three,six and twelve months is respectively was 339.73± 60.196,331.43± 52.952 m,326.2 ±53.863 in the third,sixth and twelfth months,respectively,with statistically significant differences(P<0.05).6.Correlation analysis between visual acuity changes and changes in retinal thickness in macular center: through the results We see that The difference there was no statistically significant between the best corrected visual acuity and retinal thickness in macular center in each time period(P>0.05).Conclusion:1.Qi stagnation and blood stasis type of branch retinal vein occlusion,macular edema after anti-vegf treatment,the retinal thickness in the center of macular degeneration decreased.2.Anti-vegf treatment of branch retinal vein occlusion macular edema with qi stagnation and blood stasis can effectively improve the patient’s vision.3.The better the baseline visual acuity of the patients with macular edema caused by branch retinal vein occlusion of qi stagnation and blood stasis,the better the long-term visual prognosis after anti-vegf treatment.