| Objective:The research by collecting thorough information of chronic cough in children,to determine the correlation between clinical features and etiological diagnosis,define the characteristics of TCM syndrome elements and frequently used herbs of cases of chronic cough in children,to provide evidence for TCM standardized syndrome differentiation of the disease.Methods:The research is a cross-sectional survey,it designed the clinical questionnaires of pediatric chronic cough.It collected general information by 98 cases of chronic cough in children from February 2018 to February 2019 in affiliated hospital of ※※ University of TCM(“our hpspital”for short),At the same time,99 cases of healthy children(control group)in our hospital were selected.In addition,the date of TCM syndrome elements and the traditional Chinese medicine using law were recorded.All the cases were established in the database,the data of this study were processed Excle software and SPSS20.0 statistical software.Results:1.Risk factor:Research shows,family smoking、family history and anaphylactic disease were risk factor of chronic cough in children.2.Location syndrome elements:Chronic cough disease syndrome of frequency from high to low :lung,body surface,stomach,spleen,large intestine and kidney.There was no significant difference between lung and body surface(P>0.05),and there was significant difference between the first two and the latter four(P<0.05).The former mainly combination were lung+body surface,lung+ stomach,lung+body surface+ stomach,stomach+ body surface,and stomach+ spleen.3.Nature of syndrome elements: solid nature of syndrome elements main were:wind,phlegm,heat,cold,the secondly including qi stagnation,dyspepsia,diinks,mind,dry and wet.There was no significant difference between wind,phlegm,heat,cold(P > 0.05),and there was significant difference between the first four and the latter six(P <0.05).The deficiency natures of disease of syndrome elements were Yin deficiency,qi deficiency,Yang deficiency.There was no significant difference between this three syndrome elements(P > 0.05).The combination of deficiency and solid syndrome is the main part of the disease,frequency from high to low: wind+ phlegm+ Yin deficiency,wind+ Yin deficiency+qi deficiency,wind+qi deficiency+ phlegm,Yin deficiency+qi deficiency+ heat,and there was no significant difference between this four combination(P>0.05).4.Traditional Chinese medicine using law:information of 91 cases which had exact treatment effect was collected,toltal herbs are 144 varieties,17 categories.Ranked by category from high to low:cough-suppressing phlegm-transforming medicinal,heat clearing drugs,diaphoretic drugs,tonic drugs,qi-regulating drugs,water-disinhibiting damp-percolating medicinal etc.Traditional Chinese medicine frequency from high to low were :Kuxingren,Huangqin,Banxia,Sangbaipi,Chenpi,Shegan,Mahuang,Niuban gzi,Jiegeng,Zhimu,Xuangfuhua etc.Conclusion:The results showed that family smoking 、 family history and anaphylactic disease were risk factor of chronic cough in children.Disease location syndrome elements mainly were:lung,body surface,stomach,spleen;nature of disease of syndrome elements mainly were: wind,phlegm,heat,cold and Yin deficiency,qi deficiency,Yang deficiency.The combination of deficiency and solid syndrome is the main part of the disease.The main herbs categories including cough-suppressing phlegm-transforming medicinal,heat clearing drugs,diaphoretic drugs,qi-regulating drugs etc.The location syndrome elements were closely related to nature of syndrome elements,the Traditional Chinese medicine using law is conformity with the study of the chronic cough syndrome elements.It proved that the objectivity and availability of syndrome elements differentiation,worthwhile for clinical use. |