Study On Distribution Regularity Of Zang-fu Syndrome Elements In Chronic Cough

1.Research objectiveLong cough in traditional Chinese medicine is equivalent to chronic cough in modern medicine。In this study,case information and four diagnostic data of patients with chronic cough were collected,analyze the etiology of chronic cough and the relationship with age and sex,clarify the location and combination rule of chronic cough viscera,and provide theoretical support for further improving the syndrome differentiation of chronic cough and guiding clinical prevention and treatment of the disease.2.Research methodUsing retrospective clinical investigation and research,we formulated the Questionnaire of Chronic Cough Viscera Syndrome Elements.By collecting the case information and four diagnostic data of the patients diagnosed as chronic cough from June 2017 to October 2018 in the outpatient and ward of Lung Disease Department of Shandong Traditional Chinese Medicine Hospital,combined with auxiliary examination and diagnostic treatment,etc.we entered the Questionnaire of Chronic Cough Syndrome Elements into the Questionnaire to study the risk of chronic cough.The factors and the distribution regularity of viscera disease location.The collected scale data were counted into the database,and SPSS statistical software was used to analyze and process theresearch data.3.Research results(1)Etiological Composition:This study collected 80 effective casesincluding26 cases of cough variant asthma,25 cases of post-infection cough,22 cases of upper airway cough syndrome,7 cases of chronic cough caused by other common causes(including 2 cases of gastroesophageal reflux cough,1 case of eosinophilic bronchitis,4 cases of dual and unknown causes).(2)Gender composition:The study shows that 41 males and 39 females are among80 patients with chronic cough.There is no significant difference between the total number of males and females,which indicates that the incidence of chronic cough is basically the same between males and females in the current living environment.Consider the reasons mainly with the current air,environment and living pressure caused by the decline in resistance,respiratory system damage between men and women also exist.(3)Course of disease:The study showed that among 80 patients with chronic cough,26 had a course of 2 months to 6 months,25 had a course of 6 months to 12 months,and 29 had a course of more than 12 months.Among them,cough variant asthma,upper airway cough syndrome and other causes of chronic cough are more common in the course of more than 12 months,while cough after infection is more common in the course of 2 months to 6 months.(4)Risk factors:Studies have shown that 41 chronic cough patients have smoking or family smoking history(tobacco contact history),accounting for51% of all the patients surveyed.It can be seen that tobacco contact history plays a certain role in the occurrence of chronic cough and is an important risk factor for recurrent cough and persistent recovery.To guide clinical workers in the treatment of patients with chronic cough while trying to persuade patients to quit smoking,in order to achieve better therapeutic effect.(5)Quality of life:A total of 43 patients were anxious and worried becauseof prolonged cough,accounting for 54% of the total number of patients surveyed,while 48 patients were delayed in their daily work,life and study due to cough,accounting for 60% of the total number of patients surveyed.46 of the 80 patients surveyed expressed concern about the condition and worried about the progress or change of the condition.It can be seen that prolonged cough caused by any reason has a great impact on the disease.The physical and mental health of the patients has caused great troubles to their daily life.(6)Syndrome elements of visceral diseases:The highest frequency of syndrome elements in chronic cough viscera was lung in 80 cases(100%),spleen in 51cases(63.75%),liver in 51 cases(63.75%),kidney in 28 cases(35%),stomach in 27 cases(33.75%),large intestine in 17 cases(21.25%),heart in 11 cases(13.75%),small intestine in 4 cases(5%)and bladder in 2 cases(2.5%).The results of location syndrome elements showed that the core location of chronic cough was lung,and other viscera dysfunction could also cause cough.In different etiological groups,the combination of disease location syndromes was the most frequent in three disease location combinations.There were also a small number of five disease location combinations and six disease location combinations in cough variant asthma group and upper airway cough syndrome group.4.Research conclusion(1)Etiological analysis:The main causes of chronic cough include CVA,UACS and PIC.This study shows that the etiology of persistent cough is different in different genders.CVA is the dominant cause in males,UACS is the second,PIC is the dominant cause in females,and UACS is the second.(2)Course of disease:The study showed that among 80 patients with chronic cough,26 had a course of 2 months to 6 months,25 had a course of 6 months to 12 months,and 29 had a course of more than 12 months.Long cough caused by different causes presents different distribution characteristics in the course of disease.(3)The incidence of chronic cough is correlated with the history of tobacco exposure.At the same time,the occurrence of chronic cough has a significant impact on the physical and mental health of patients.(4)The results showed that lung,liver and spleen were the main sites of chronic cough,while kidney,stomach,large intestine,heart,small intestine,bladder and other viscera were equally important in the pathogenesis of cough.