| Objective:To observe the effect of clinical Pharmacists on the efficacy of Pharmacological interventions in the treatment of community-acquired Pneumonia(CAP)in children with oxygen aerosol inhalation,and to explore the role of clinical Pharmacists in the implementation of Pharmacy interventions in the treatment of CAP in children with oxygen aerosol inhalation.Methods:Patients with CAP and complicated with asthma and suffocation from 2-7 years old in our hospital from October to December 2017 and from October to December 2018 were included in the clinical observation 170 children who met the inclusion and exclusion criteria were divided into control group and experimental group.In January 2018,our had began to carry out clinical pharmaceutical care in pediatric department.We participated in pediatric ward rounds,doctor’s advice examined,adverse reactions monitoring and standardized atomization inhalation.In order to understand the effect of intervention before and after oxygen atomization inhalation,we selected common pediatric pneumonia patients as observation objects.Because of the high incidence of pneumonia in winter and spring season,we chose October-December 2017 and 2018 as the same season comparison.85 Patients who were admitted from October to December 2017 as a control group were given conventional oxygen atomization on the basis of anti-infective and symptomatic treatment.85 patients who were admitted from October to December 2018 as an experimental group were given oxygen atomization under Pharmacy intervention on the basis of anti-infective and symptomatic treatment.This study compared differences in vital signs,clinical outcomes,and adverse effects between the two groups before and after treatment.Results:1.The intervention of clinical Pharmacists in the inhalation therapy of oxygen atomization in children with CAP has significant effect on the Patient’s temperature change,the average body temperature of the experimental group was 2.36 days,which was significantly better than that of the control group(1.64 days).The difference was statistically significant(P<0.05).2.After 3 days of aerosol therapy,the effects of the two groups were compared before and after treatment.There was no significant difference between the two groups(P>0.05),but the effective rate of cough symptoms(95.29%)in the experimental group was slightly better than that of the control group(88.23%).The clinical Pharmacist intervention group manages the details of oxygen flow,atomization timing,body Position,and diluent.It can improve the symptoms of cough in children and improve the effect of nebulization,but the degree of improvement is not very satisfactory.3.After 3 days of treatment,the lung auscultation scores of the two groups were compared.There was no significant difference between the two groups(P>0.05),but the cure rate of the experimental group(89.41%)was slightly higher than that of the control group(84.71%).This indicates that the clinical Pharmacist intervention in children’s CAP oxygen aerosol inhalation has a certain improvement in the Patient’s lung auscultation,but not obvious.4.There were no significant differences in white blood cell counts and C-reactive Protein between the two groups after 3 days of treatment.The difference was not statistically significant(P>0.05).5.The cost of Western medicine was compared between the two groups.There was no significant difference between the two groups(P>0.05).The cost of western medicine in the experimental group was slightly lower than that in the control group.The cost of western medicine in the experimental group was 41.37 yuan lower than that of the control group,and the reduction rate was 6.18%,the average cost of antibiotics per capita in the experimental group was 272.77 yuan,which was significantly lower than 384.33 yuan in the control group(P<0.05).The incremental-effect analysis of the two groups showed that the cost of the control group and the health output obtained were lower than the test group compared with the test group,and the test group was the superior program.6.There was no significant difference in the overall efficacy and average length of stay in hospital between the two groups after discharge,which was not statistically significant(P>0.05).However according to different hospitalization time groups,the cure rate was significantly different between the two groups(P<0.05),the cure rate of the experimental group was significantly higher than that of the control group,and the number of cases improved in the two groups was significantly different(P<0.05),the number of cases in the experimental group was significantly better than that in the control grouP.7.Incidence of adverse reactions in the Clinical Pharmacist Intervention Group(10.59%),was significantly lower than that in the control group.Adverse reactions between the two groups was significantly different(P<0.05).The results showed that the intervention of clinical Pharmacists on oxygen atomization in children with Pneumonia could significantly reduce the incidence of adverse reactions caused by oxygen atomization inhalation.Conclusion:1.The intervention of the clinical pharmacist can significantly shorten the normal temperature of the patient’s body temperature,and has no obvious effect on the symptoms of cough and lung auscultation,but there is an improvement trend,and there is no obvious influence on the auxiliary examination.The treatment effect is compared according to different hospitalization days.The cure rate was significantly higher than the control group,but the overall efficacy was not significantly different.2.The intervention of clinical pharmacists can significantly reduce the cost of antibacterial drugs,and it has a certain reduction effect on the cost of western medicine,but it is not obvious,and it cannot be excluded from the inclusion of fewer cases.3.Incidence of adverse reactions in the Clinical Pharmacist Intervention Group,was significantly lower than that in the control group.Adverse reactions between the two groups was significantly different.In a word,strengthening the medical services of oxygen atomization inhalation can reduce adverse reactions and increase patients’compliance,and improve the clinical efficacy of atomization drugs to a certain extent. |
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