Effect Of Assessment Of Disease Activity In Patients With RA

Background and Objective Rheumatoid arthritis(RA)is a chronic,systemic autoimmune disease characterized by invasive symmetrical multiple arthritis.The typical pathological manifestations were synovitis,pannus formation and bone destruction.The prevalence of RA in global was 0.5% to 1%,and there’s no regional difference.The incidence of RA in women is about three times as high as in men.At present,The definite pathogenesis and etiology are still unclear.Most scholars believe that the combination of genes and the environment causes the disorder of the immune system.Although RA can not be completely cured at present,the existing methods for RA can effectively control the disease,achieve clinical remission or low disease activity,and then delay the progress of the disease.The goal of treatment is not only to soothe inflamed joints,but also to slow joint destruction,improve quality of life and prolong survial.The Treat to target of RA have gradually been accepted and recognized widely.Patients’ disease activity score as the main index in the promotion of Treat to target piaying an important role in the choice of drugs for clinical treatment.currently,The disease activity scores of RA was assessed by doctors,and it was unrealistic to assess all patients duing to the time limitation in the clinic.The improvement in the average level of education and the popularity of smart phones make it possible for patients to assess their disease activity score.The objective of the research is to explore the value of assessment of disease activity in RA individuals’ target control.Methods:According to the RA diagnostic criteria established by ACR/EULAR in 2010,94 patients were eligible for the study.All the patients were treated in our hospital for the first or the current condition is getting worse in this study.They were divided into a patient assessment group(group A),a doctor assessment group(group B),and an unevaluated group(group C).Training of patients in the group A in the assessment of disease activity,and urge this group of patients to evaluate the disease before diagnosis.The disease activity in group B was assessed by the physician.Based on the results of the assessment,the treatment of patients in group A and group B will be adjust.The patients in group C were treated according to the clinlcal symptoms of the patients.The patients’ age,sex,course of disease and other general data were collected at the time of entering the group.The number of tender joints and swelling joints and other clinical data were recorded during the first visit and one year after treatment.The primary assessment criterion was the DAS28 evaluation system,Depending on the primary outcome measure,remission was defined as DAS28 <2.6,target control was defined as DAS28-ESR score match with remission or low disease activity.The secondary assessment criteria were American College of Rheumatology(ACR)、clinical disease activity index(CDAI)and the Health Assessment Questionnaire score(HAQ).Result1.A comparative analysis of the general data of the patient assessment group,the doctor evaluated group and the non-evaluation group showed that there was no statistical difference in age,sex and course of disease between the three groups(p>0.05).2.There was no significant difference in the remission rate of RA between the patients assessment group and the doctor evaluation group(p < 0.05).3.There was a significant difference in the remission rate of RA between the evaluation group and the unevaluated group(p < 0.05).4.There was a significant difference in remission rate of ra between the doctors’ evaluation group and the unevaluated group(p < 0.05).Conclusion:1.Evaluation of disease activity in the course of treatment is beneficial to the prognosis of the patient.2.Patient self-assessment and physician assessment can also be used to guide clinical treatment.