Clinical Study On The Treatment Of Non-Small Cell Lung Cancer-Related Depression And Sleep Disorder By Sanhua Jieyu Anshen Decoction

ObjectThis article through clinical trials,starting from the perspective of prevention and treatment,combining disease differentiation and syndrome differentiation,with the idea of “soothing the liver and relieving depression and tranquilizing the anesthesia”,compose “Sanhua Jieyu Anshenfang” to treat non-small cell lung cancer-related depression and sleep disorders.,Observe changes in indicators such as Hamilton Depression Scale(HAMD)(see Attached Table 1)and Pittsburgh Sleep Quality Index(PSQI)(see Attached Table 2)in the control and experimental groups.The effectiveness of treatment of depression-related depression and sleep disorders and the impact on the quality of life of cancer patients.Observing the clinical curative effect of integrated traditional Chinese and western medicine intervention in the treatment of depression-related depressive states and sleep disorders provides a theoretical and practical reference for the standardized treatment of traditional Chinese medicine tumors and the participation of TCM subjects in the multidisciplinary collaborative treatment(MDT)model of tumors.MethodsAccording to a randomized controlled trial,58 patients with non-small cell lung cancers complicated with depression and sleep disorders who were hospitalized in Shanxi Provincial Integrative Medicine Hospital between January 2017 and January2018 were observed.Randomly divided into experimental group of 30 cases,control group of 28 cases,two groups of patients based on evidence-based standardization of surgery,radiotherapy and chemotherapy,targeted therapy,nutritional support and other treatment,are routinely used escitalopram oxalate tablets for antidepressant For treatment,the experimental group added Sanhua Jieyu Anshen Fang on the basis of the control group.Statistical analysis was used to compare the data of patients’ gender,age,and course of disease.Data on the HAMD scores and PSQI scores before and after treatment were statistically compared.Results1 Basic situation: There was no statistical difference in gender,age,and course of disease between the experimental group and the control group(P>0.05).2 HAMD scores showed that most of the patients in the study group were mild to moderate depression,and the patients in the treatment group were compared with those in the control group.It showed that the overall effect of relieving rate ofdepression-related symptoms by Chinese and Western medicine treatment was more significant.3 PSQI scores showed that most of the patients in the study had sleep disturbances.Compared with patients in the control group,the patients in the treatment group showed that the overall effect of the combination of Chinese and Western medicines in treating sleep disorder related symptoms was more significant.ConclusionCompared with escinopram oxalate alone,Sanhua Jieyu Anshenfang combined with escitalopram oxalate has better effects on resolving depression-related symptoms and improving sleep disorders.