| ObjectiveTo evaluate the clinical efficacy of Yiqi Tongyu Decoction in the treatment of benign prostatic hyperplasia(spleen and kidney qi deficiency type),and provide effective methods and broad ideas for the treatment of BPH by Chinese medicine.MethodsSixty-four patients with benign prostatic hyperplasia(spleen and kidney qi deficiency)from March 2017 to May 2018 in the Department of Traditional Chinese Medicine and Urology Surgery and Inpatient Department of Wuhan Central Hospital were selected and randomly divided into treatment group and observation.Group,32 patients in each group.The observation group was treated with tamsulosin hydrochloride sustained-release capsules.The treatment group was treated with Yiqi Tongbi Recipe on the basis of the treatment of the observation group.The Chinese Herbal Pieces and Decoctions were uniformly provided by Hubei Tianji Traditional Chinese Medicine Pieces Co.,Ltd.,1 dose per day,2 After/after the meal,take about 200 ml each time.Both groups were treated with continuous medication for 8 weeks.TCM symptom scores,international prostate symptom score(IPSS),quality of life assessment(QOL),maximum urinary flow rate(Qmax),prostate volume(PV),and residual were assessed before and after treatment.Urine(RU),the data obtained were statistically analyzed using SPSS 22.0software.Result1.During the observation,the treatment group was detached in 1case,1 case was excluded,and 30 cases were actually completed.In the observation group,2 cases were detached and 30 cases were actually completed.After 8 weeks of treatment,in the clinical symptoms,the two groups of patients had significant improvement in the main symptoms such as urination weakness,urinary waiting,frequent nocturnal urination before treatment,P<0.05 compared with before treatment,the difference was statistically significant.There was no statistical difference between the groups,P>0.05.However,in the secondary symptoms such as less abdominal distension,weak waist and knees,fatigue and fatigue,and poor food intake,the treatment group was significantly improved compared with before treatment,P<0.05.The difference was significant,but the observation group had no significant improvement compared with before treatment,P>0.05,no significant difference.There was significant difference between the two groups(P<0.05).2.In the efficacy of TCM syndromes,the total scores of TCM syndromes in the two groups were significantly lower than those before treatment,P<0.05,there was a statistical difference,P<0.05 between the groups after treatment,the difference was statistically significant.In the total efficacy of TCM syndrome,the effective rate of the treatment group was 93.33%,and theeffective rate of the observation group was 70%.There was a statistical difference between the two groups(P<0.05).3.In the changes of IPSS and QOL,the IPS and QOL of the two groups were significantly improved compared with those before treatment,P<0.05,and the improvement of the treatment group was better than that of the observation group after treatment,all P<0.05,statistically significant.4.In the improvement of Qmax,the Qmax of the two groups was significantly higher than that before treatment,P<0.05,the difference was statistically significant,while the treatment group was more obvious than the observation group,P<0.05,the difference was statistically significant.5.Before and after treatment,the PV of the two groups were compared.After treatment,the PV of the treatment group was lower than that before treatment,P<0.05,there was statistical difference,but the observation group had no significant improvement compared with the PV before treatment,P>0.05,no statistics.The difference was P<0.05 between the groups after treatment.6.In the improvement of RU,after treatment,the RU of the two groups were significantly decreased compared with those before treatment,P<0.05,the difference was statistically significant,and the improvement of the treatment group was better than that of the observation group after treatment,all P<0.05.There are statistical differences.7.The safety indicators were evaluated.Before and after treatment,the two groups of patients improved blood routine,bowel movement routine,liver and kidney function and electrocardiogram.The results showed no adverse reactions such as liver and kidney dysfunction,obvious abnormal electrocardiogram,and other treatments.The patient’s body temperature,pulse,heart rate,blood pressure and other general vital signs were detected separately,and no abnormalities in vital signs occurred.ConclusionOn the basis of routine treatment of Western medicine,the application of Yiqi Tongyu Recipe can significantly improve the main symptoms of urinary insufficiency,urinary waiting,frequent nocturia,etc.,and can significantly improve the lower abdominal bulge,weak waist and knees,fatigue and fatigue.Less negative symptoms and other secondary symptoms,and can reduce the patient’s PV to a certain extent,can better improve the IPSS and QOL score,improve Qmax,reduce RU,significantly improve the degree of bladder outlet obstruction,thereby improving the quality of life of patients,and in the short term There are no obvious side effects and safety is good. |