Analysis Of Antihypertensive Drugs In Outpatient Clinic Of A Grade 3A Hospital In Northern Mountain Area Of Tianjin

Objective:Survey of tianjin in northern mountainous area of a tertiary hospital outpatient antihypertensive drug electronic prescription,analysis the clinic epidemiological characteristics of hypertension crowds,analysis of hypertension with coronary heart disease,cerebrovascular disease,renal insufficiency and the standardization of the diabetes drug,analysis combination,commonly used antihypertensive drug,commonly used antihypertensive scheme and guide.Promote hypertension management and improve the level of rational drug use,drug treatment for clinical medical workers selected drugs to provide references and scientific basis.Methods:Tianjin northern mountains a tertiary hospital in 2014 were retrospectively analyzed in January-December electronic prescription,17900 cases of outpatient high blood pressure.Statistics of each patient’s gender,age,diagnosis,complications,medications,according to patients’ age,gender and grade of hypertension,prescription drugs,complications;The WHO recommends DDD analysis statistics of all kinds of antihypertensive agents in frequency(DDDs),average daily costs(DDDc),calculate drug utilization index(DUI).Results: 1.with the increase of age,hypertension outpatient prescriptions of increase,before the age of 60 women more than men,men and women at the age of 60-70.2.Patients with an average age of 55.24±15.46 years,including 65-year-old patients(26.1%)or higher,each prescription antihypertensive drugs for 1 ~ 7 kinds of species number,the average prescription medicine 1.30 ± 0.522).Calcium antagonists for outpatient service for patients with high blood pressure,the most common medicine.3.Antihypertensive combination ratio significantly lower than monotherapy,monotherapy hypertension utilization rate of 72.23%.Elderly group combination is higher than the elderly group,single drug is lower than the elderly group.Level 3combination therapy of hypertension is higher than grade 2 and grade 1 hypertension,general internal combination is higher than other department..4.Outpatient service of the most commonly used antihypertensive drug for calcium ion antagonist(53.88%),and the rest of angiotensin II receptor antagonist(21.39%),angiotensin converting enzyme inhibitors(11.07%),fixed compound preparations(4.17%),diuretics(3.2%),beta blockers(0.17%).Associated with complications of hypertension is the most commonly used antihypertensive agents calcium antagonists.ACEI/ARB in merger is more,with the use of beta blockers and diuretic complications in patients with high blood pressure is less use of drugs.5.Commonly used antihypertensive scheme is given priority to with single-agent therapy(72.23%),with calcium ion antagonist used most(48.78%),followed by angiotensin II receptor antagonist(12.46%).Combination scheme is given priority to with two couplet medicines(20.23%),the most commonly used two couplet regimen for calciumion antagonist + angiotensin II receptor antagonist,calcium channel blockers and angiotensin converting enzyme inhibitor,unreasonable combination of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonist(3.58%).Sanlian and contains more than triple regimen diuretics(including fixed compound preparations contain diuretics)accounted for only 4.16%.6.DDDs sequencing of all kinds of antihypertensive drugs for CCB,ARB and ACEI,beta blockers,diuretics,traditional Chinese medicine(TCM),fixed compound preparations.DDDs sequencing of the top five is valsartan dispersible tablets,sinistral amlodipine maleate,candesartan ester,fu cinepolis,tartaric acid metoprolol,the sum of the top five is sinistral amlodipine maleate and valsartan dispersible tablets,nifedipine controlled-release tablets,candesartan ester,f cinepolis,average daily cost of the top five are nifedipine controlled-release tablets and valsartan capsules,sinistral amlodipine maleate,benzene sulfonic acid amlodipine,diltiazem.Conclusion:Studies have shown that outpatient hypertension patients age and gender in line with the epidemiological characteristics of hypertension in China.Calcium antagonists are the most commonly used outpatient antihypertensive agents,consistent with our guide,diuretics,fixed compound preparations with a guide gap.Combination ratio is low,some drug use overdosage phenomenon,should be more attention from clinical doctors,notice reasonable,standardize the use of antihypertensive drugs.