Clinical Study On Jiawei Tongxie Yaofang In Treating Diarrhea Predominant Irritable Bowel Syndrome(Liver Depression And Spleen Deficiency Syndrome)

Objective: To observe the clinical treatment effects of Jiawei Tongxie Yaofang on patients with irritable bowel syndrome,diarrhea and liver stagnation and spleen deficiency syndrome,objectively evaluate its clinical efficacy and safety,and provide basis for Chinese medicine treatment IBS.D optimization program for clinical promotion and application.Methods: Using the randomized,controlled principle,60 patients with IBS.D who met the criteria were randomly divided into the treatment group and the control group with 30 cases each.Questionnaires were used to record the indicators of patients before treatment.The control group was given pinaverium bromide tablets,50 mg,3times a day;montmorillonite powder,3g,3 times a day;Bifidobacterium quadruple live bacteria tablets,1.5g,3 times a day;the treatment group was given Jiawei Tongxie Yaofang,2 times a day,taking 4 weeks as a course of treatment,a total of 1course of treatment.After the end of the treatment,each index of the patient’s follow-up and 8 weeks’ follow-up was recorded.The symptom scores and safety indicators of the two groups of subjects were analyzed and compared to evaluate the clinical efficacy of Jiawei Tongxie Yaofang in the treatment of IBS.D.The study data using SPSS22.0 software,P<0.05 was considered statistically significant,P<0.01 was statistically significant.Results:(1)The gender,age,course of disease,and scores of primary and secondary diseases before treatment in the two groups were analyzed statistically,P>0.05,and there was no statistical significance,indicating that the two groups of data were comparable.(2)Clinical total curative effect: the treatment group: 1 recovered,14 markedly effective,14 effective,1 invalid,the total effective rate was 96.67%;the control group:0 cured,5 marked,18 effective,7 invalid,the total effective rate was 70%.Statistical analysis of the two groups of data,P<0.05,the difference was statistically significant,indicating that the treatment group has obvious advantages over the control group in improving clinical symptoms.(3)The main symptoms: Both groups can significantly improve the main clinical symptoms,and the long-term effect is significant.In improving stool frequency,the curative effect and long-term curative effect of the treatment group were better than those of the control group.The curative effect of the treatment group was better than that of the control group in terms of improving stool characteristics,abdominal pain,and lower abdomen.However,there was no significant difference in the long term efficacy between the two groups.(4)Secondary symptoms: Both groups can effectively improve the secondary clinical symptoms,and the long-term efficacy is obvious.In terms of improving bloating and mucous flushing,the two groups had similar results,but the long-term efficacy of the treatment group was significant.In the improvement of bowel gas and emotional factors,the treatment group had a clear advantage over the control group,but there was no difference in the long-term efficacy between the two groups.(5)No significant adverse reactions occurred in both groups of patients during the course of treatment.(6)Long-term efficacy: the treatment group: 0 cured,7 markedly effective,19 effective,4 ineffective,the total effective rate was 86.67%;the control group: 0 cured,1 marked,18 effective,11 invalid,the total effective rate was 63.33%.Both statistical analysis,P<0.05,there was significant difference,indicating that in the improvement of clinical symptoms,the long-term efficacy of the treatment group was better than the control group.Conclusion: Jiawei Tongxie Yaofang can significantly reduce the clinical symptoms of patients with IBS.D and relieve the clinical pain of patients.Its comprehensive curative effect and long term curative effect are significant without obvious adverse reactions.(1)Jiawei Tongxie Yaofang has significant curative effect,can reduce the clinical symptoms of patients and improve the clinical diagnosis and treatment rate.(2)Jiawei Tongxie Yaofang has no serious adverse reaction and has high safety.