Risk Factors Of Obstructive Sleep Apnea-Hypopnea Syndrome Patiens With Pulmonary Embolism

Objective: This paper focuses on research into the risk factors of obstructive sleep apne-a-hypopnea syndrome(OSAHS)patients with pulmonary embolism(PTE).Methods: A 1:1 pair-matched case-control study was conducted in 59 cases of OSAHS with PTE and 59 cases of OSAHS age-sex-matched controls were treated in this hospital from January 2010 to October 2017,The general clinical datas and the results of Polysomnography were collected in all subjects.Univariate analysis was conducted to determine the possible associated variables.Conditional logistic regression analysis was applied to explore risk factors of obstructive sleep apne-a-hypopnea syndrome(OSAHS)patients with pulmonary embolism(PTE).Results: Results were significant differences in BMI,dyslipidemia,pulmonary hypertension,red blood cell count,fibrinogen(Fib)and D-dimer levels between the two groups(P<0.05)..PSG results showed that two groups patients in average blood oxygen saturation,apnea-hypopnea index(AHI),the longest pause time(SAmax)comparative differences are statistically significant(P < 0.05);Multivariate conditional logistic regression analysisshowed that BMI、 apnea-hypopnea index(AHI),the longest pause time(SAmax)comparative differences are statistically significant(P < 0.05);Multivariate conditional logistic regression analysis showed that BMI(OR = 14.707,p = 0.019),red blood cell count(OR = 11.938,p = 0.021),D-dimer(OR = 18.00,p = 0.025)and AHI(OR = 5.946,p = 0.018)were risk factors for obstructive sleep apne-a-hypopnea syndrome with pulmonary embolism.Conclusion: BMI or higeher blood cell count、D-dimer、AHI were risk factors for obstructive sleep apne-a-hypopnea syndrome with pulmonary embolism.,There was significant statistical significance.