| Objective 1.To investigate the status of clinical control after inhalation treatment in asthmatic children in this area,and to explore the influencing factors of uncontrolled asthma inhalation therapy in children.2.To investigate the clinical efficacy and pulmonary function changes after intervention of the above-mentioned influencing factors,so as to provide basis for raising the asthma control level in the future.Methods 1.From December 2015 to December 2016,we studied 230 children with asthma who visited the Pediatric Asthma Clinic in XX Hospital.Patients who met the inclusion criteria and agreed to participate in the study were included in the survey.Asthmatic outpatient specialists were divided into complete control group,partial control group and uncontrolled group according to asthma control standard.All subjects completed questionnaires on asthma control in children with 23 possible related factors.Statistics were made for all three groups of children,and univariate analysis and Logistic analysis were used to identify the influencing factors that affected the clinical uncontrolled asthma in children.2.In the above studies,some control groups and uncontrolled groups were selected as the study subjects,and those with a single influencing factor were selected as the intervention targets.Targeted interventions were taken for different influencing factors to observe c-ACT scores,daytime symptoms,nighttime symptom scores,and pulmonary function changes at 4 weeks,8 weeks,and 12 weeks after intervention.All collected data were statistically analyzed in SPSS 19.0 software,including descriptive analysis,t-test,2 test and rank sum test,single factor analysis and Logistic regression analysis.Results 1.A total of 240 cases were collected,and 230 cases were valid.A total of 230 children with asthma were studied.The total control rate of asthma was 64.8%,the partial control rate was 27.8%,and the uncontrolled rate was 7.4%.2.Comparison of the complete control group,some control groups and uncontrolled groups,statistical differences in age,rhinitis,ICS compliance,ICS operating practices,recent renovations,and obesity in the three groups(p<0.05),univariate analysis The logistic regression analysis of uncontrolled influencing factors in children's inhalation therapy was age(OR=4.574,P=0.01,95% CI:1.818-11.508)and rhinitis(OR=4.319,P=0.01,95% CI: 1.832-10.182).),ICS compliance(OR=0.133,P=0.00,95% CI: 0.056-0.317),ICS protocol(OR=0.321,P=0.008,95% CI: 0.139-0.741).3.According to the uncontrolled clinical factors that affect asthmatic asthmatic children: rhinitis,ICS compliance,and ICS operating practices,three groups were selected.In the rhinitis group,the ICS compliance group,and the ICS protocol group,the c-ACT score,daytime symptoms,and nighttime symptom scores were statistically different from those before the intervention at 4 weeks,8 weeks,and 12 weeks.There was a statistically significant difference between the c-ACT score and the daytime symptoms at 12 weeks,8 weeks,and 4 weeks.Nighttime symptoms were statistically significant between the 12 weeks,8 weeks,and 4 weeks groups,but there was no significant difference in between 12 weeks and 8 weeks.After 12 weeks of intervention,the changes of lung function between the three groups of patients were significantly.Conclusions 1.Age,rhinitis,ICS compliance,and ICS practices are influential factors for the uncontrolled clinical use of asthma in children.2.Targeted interventions can improve asthma control,improve daily and nighttime symptoms,and improve lung function. |
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