Objective:Evaluation at large fructus Xiao yao lou bei capsules in the treatment of mammary gland ill liver depression TanNing clinical curative effect,provide the basis for further clinical trials.Methods:Choice of mammary gland hyperplasia patients of 100 cases were randomly divided into treatment group and control group 50 cases each.Treatment group: to give free and unfettered fructus Xiao yao lou bei capsule treatment,3 pills each time,3 times/day,with warm water.Control group: Ru pi san jie capsules,(shaanxi white hart pharmaceutical co.,LTD.,approved by: Z20010010,specifications: 0.53 g * 60)Usage and dosage: oral,4at a time,three times a day.Two groups of patients with continuous dosing respectively in March,menstruation stop taking.The make a record before and after the treatment,3months for one period of treatment,record all cases subjects during the stop using other drugs.Results:1.The total effective rate was 90% in treatment group,control group total effective rate was 72%,the treatment group was better than control group,two groups of curative effect compared with significant difference(P < 0.05).2.The two groups after treatment of TCM syndrome total integral group,differences were significant(P <0.01);Two components after the treatment,comparison(P < 0.05),the differences were significant.3.The two groups after treatment of TCM primary symptom integral group,differences were significant(P < 0.01);Comparison between the two way after treatment,there are significant differences(P < 0.05),the treatment group can improve the main symptoms of breast,its effect is better than the control group.4.Within two secondary symptom group after treatment,the differences were significant(P < 0.01),after treatment between the two way comparison,there are significant differences(P < 0.05),the treatment group can improve the symptoms of secondary,and the effect is better than the control group.5.Two groups of patients after treatment in the ultrasound imaging group comparison(P <0.05),there is significant difference;Comparison between groups after treatment(P > 0.05),there was no statistically significant difference.6.The two groups after treatment in patients with color doppler flow imaging group comparison(P > 0.05),treatment group(P > 0.05),and is compared between the there wasno statistically significant difference,improve blood flow signals in the effect is not obvious that the two group.7.The thickness of the two groups of patients with bilateral breast glands after treatment group comparison(P<0.05),there is significant difference;Bilateral breast glands thickness comparison between groups after treatment(P > 0.05),there was no statistically significant difference.Conclusion: This clinical trial results shows that: Xiao yao lou bei capsules can treat hyperplasia of mammary glands(liver depression TanNing type)with liver resolve depression,phlegm fights the role of,can alleviate pain in patients with breast,shrink breast bump,improve mass texture,can be a very good improve patients with symptoms,curative effect,high safety. |