To Evaluate The Clinical Efficacy Of Chronic Heart Failure Based On "qi And Blood Theory"

Purpose : This study aims to observe Yiqi Huoxue traditional Chinese medicine clinical therapeutic effects on patients with chronic heart failure, through the use of supplementing Qi and activating blood circulation herbs in the treatment of qi deficiency and blood stasis type of chronic heart failure(heart function II, III); To prove "the clinical curative effect of supplementing Qi and activating blood circulation" method in the treatment of chronic heart failure, through comparing the change of each index; To illustrate the relationship of "Qi blood theory" and the pathological mechanism of chronic heart failure; To reveal "Yiqi Huoxue" method in the treatment of chronic heart failure and to provide a new thought about the relationship between pathogenesis essence to further clarify the "Qi Theory" and CHF.Materials and methods:In this experiment, all the subjects were derived from the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine and Liaoning traditional Chinese medicine rehabilitation center from January to December 2014 or hospitalized patients who met the inclusion criteria of chronic heart failure. All cases, in total of 82 according to their visiting order, were randomly divided into the treatment group and the control group, 41 cases of each. The control group was with conventional Western medicine treatment, while the treatment group was given Chinese medicine of supplementing Qi and activating blood circulation on the basis of conventional treatment(including Astragalus, ginseng, safflower, danshen root, motherwort, poria, and semen Lepidii). The observation time was one month. Two groups were observed: before and after the treatment in patients with heart failure curative effect of ECG, integral(using Lee’s), heart function, heart function index, TCM syndrome integral, 6 minutes of walking distance, quality of life scale andhydrochlorothiazide withdrawal rate changes, and recorded the basic vital signs of patients and adverse reaction during treatment. Follow up after sixth months of treatment.Results:1.General information: comparing between the two groups before and after the treatment in gender, age, course of disease, disease, heart failure curative effect score based distribution, classification of cardiac function, cardiac function index, TCM syndrome integral, 6 minutes of walking distance, quality of life scale score, there was no significant difference(P > 0.05), illustrating that two groups of patients were comparable.2.ECG: after the treatment, the total efficiency of two groups of ECG was improved, with the significant of difference(P < 0.05), comparing between the two groups ’ ECG significant efficiency, efficiency, inefficiency, the deterioration rate, constituent ratio of different, with statistical significance(P < 0.05).3.Heart failure curative effect of integral:heart failure curative effects were compared between two groups before and after the treatment of heart failure curative effect score, with the significant difference(P < 0.01). After treatment, the treatment group and the control group with heart failure had significant difference(P < 0.05), and the treatment of integral group Heart Failure Efficacy was better than the control group(P < 0.05).4.Cardiac function classification: classification of cardiac function after treatment, heart function of two groups the total efficiency compared with significant difference(P < 0.05), and cardiac functions were compared between the two groups: significant efficiency, efficiency, inefficiency, the deterioration rate, constituent ratio of different, with statistical significance(P < 0.05).5.The heart function index: after the treatment, compared two groups of ESV, no statistical significance(P > 0.05); two groups of EDV, SV and EF value, with significant difference(P < 0.05); compare the mean values of two groups of EDV, SV and EF before and after treatment(P < 0.05),there is statistical differences.6.TCM syndrome integral: curative effect between two groups before and after the treatment of heart failure points, all have significant difference(P < 0.01);after treatment, two groups of TCM syndrome integral total efficiency comparison, no significant difference(P > 0.05); but the treatment group and the control group markedly effective, efficient, no comparison of efficiency, the constituent ratio of different, with statistical significance(P < 0.05). Two groups of TCM syndrome integral improvement situation are different.7.6 minutes of walking distance: the two groups were compared before and after treatment 6min walking distance, the treatment group and the control were significantly different(P < 0.01), the two groups after treatment can increase the 6min walking distance; after treatment, the two groups had significant difference(P < 0.01), and the treatment group was superior to control group.8.Quality of life scale scores: the qualities of life scale scores were compared between two groups before and after treatment. Quality of life scale score, there were significant differences in sex(P < 0.01);After treatment, the two groups was statistically significant(P < 0.01), two groups can improve the life quality of the patients, and improving effect of treatment group significantly better than the control group.9.Hydrochlorothiazide was stopped: after the treatment, compared two groups with statistical difference(P < 0.05).Conclusion:1.Yiqihuoxue Chinese herbal medicine, combined with conventional western medicine foundation treatment, can significantly improve the chest ability in patients with chronic heart failure(boring) clinical symptoms of pain, fatigue, shortness of breathe, palpitation etc. Confirmed "consistent with Qi deficiency and blood stasis pathogenesis essence qi blood theory" and chronic heart failure.2.Yiqihuoxue Chinese medicine can significantly reduce the integral effect of chronic heart failure patients(Qi deficiency blood stasis type) II and III of the heart function, improve the effect of heart failure, reduce left ventricular end diastolic diameter and left ventricular end systolic diameter, improve ventricular structure, increase the stroke volume and ejection fraction, improve heart function, improve the classification of heart function, enhance the patient’s exercise tolerance, improve survival quality, and reduce the rate of use of diuretics.3.The course of treatment showed no obvious or serious adverse reactions and side effects, safe and effective treatment, and is worthy of wide clinical application.