The Clinical Observation Of Treating Pre‐diabetes(Qi And Yin Deficiency With Phlegm And Blood Stasis Syndromes) By Yangshen Qingtoudaoxie Decoctiong

Purpose: This study "Pathogenic factors hidden in the Sangao" as the theoretical basis,adopting Yangshen Qingtoudaoxie Decoction treating pre-diabetes qi and Yin deficiency with phlegm and blood stasis syndromes,with random grouping method through clinical observation,supplementing qi and nourishing yin,resolving phlegm,remove blood stasis,and eliminating pathogens from exterior safety and effectiveness of this evil treatment,early prevention and treatment of diabetes early,early prevention of diabetes with new ideas and new methods,create a new situation to reverse diabetes.Method: Selection of Changchun University Hospital of Traditional Chinese Medicine affiliated hospital the department and department of outpatient and hospitalized patients with diabetes treatment area to meet the requirements of dialectical grouping people with pre-diabetes,strict control of reasonable diet,exercise,the treatment group to Yangshen Qingtoudaoxie Decoction,the control to acarbose tablets,continuous observation of clinical symptoms,waist circumference,BMI index,serum insulin,blood glucose,insulin resistance,insulin sensitive index,the index of beta cell function index 3 period of treatment,such as 4 weeks for a course of treatment.Primary clinical observation of 72 cases,randomized controlled method to divide two groups,after strict screening cases fall off the remaining standard cases for treatment group and control group 30 cases.Result: Statistical analysis of pre-diabetes qi and Yin deficiency with phlegm and blood stasis syndromes in 60 cases.Clinical symptoms of the total effective rate of ginseng clear guide evil soup treatment group was 86.67%,acarbose control group 43.33%;Clinical symptoms integral comparison,Chinese traditional medicine group of the main symptoms of patients with all had significant improvements,acarbose only improve the "dry mouth much drink"(P < 0.05),other symptoms not seen improved(P > 0.05);FPG,2 HPG,HbA1 c,two groups were improved significantly(P < 0.01),while in the aspect of the improvement of the FPG Chinese medicine group was obviously better than acarbose group(P < 0.01);Both groups can significantly improve the body weight,waist circumference,BMI level(P < 0.01);Effect of FINS to improve the level of two groups were significantly(P < 0.01),while Chinese medicine group is better than that of acarbose group(P < 0.01);HBCI,IAI,HOMA IR in the two groups have improved significantly(P < 0.01),ginseng clear guide in the aspect of improving HBCI,IAI evil soup group was obviously better than acarbose group(P < 0.01).Clinical symptoms integral comparison,Chinese traditional medicine group of the main symptoms of patients with all had significant improvements,acarbose in addition to improve the "dry mouth much drink"(P < 0.05),other symptoms not seen improved(P > 0.05);FPG,2 HPG,HbA1 c,two groups were improved significantly(P < 0.01),while in the aspect of the improvement of the FPG Chinese medicine group was obviously better than acarbose group(P < 0.01);Both groups can significantly improve the body weight,waist circumference,BMI level(P < 0.01);Effect of FINS to improve the level of two groups were significantly(P < 0.01),while Chinese medicine group is better than that of acarbose group(P < 0.01);HBCI,IAI,HOMA IR in the two groups have improved significantly(P < 0.01),in the aspect of improving HBCI,IAI Yangshen Qingtoudaoxie Decoction group was obviously better than acarbose group(P < 0.01).Conclusion: This clinical study of ginseng clear guide evil soup with acarbose can effective hypoglycemic;Yangshen Qingtoudaoxie Decoction in reduced fasting blood glucose,improve clinical symptoms,protect beta cell function and insulin sensitivity significantly superior to acarbose;Reflect the long-term meaning of the theory of "cure not ill",decrease incidence of diabetes.