| Objective: To investigate the epidemiological features and analyze the related risk factors of Allergic rhinitis(AR)in Guiyang.The purpose is to provide a reference in the prevention and treatment of allergic rhinitis in Guiyang.Methods: All samples were randomly selected by the multi-stage stratified cluster sampling method : Four districts/cities(Qingzhen City,Yunyan,Nanming and Huaxi District)were randomly selected from the ten districts/cities/countries(Yunyan,Nanming,Huaxi,Wudang District,Baiyun District,Guan Shan Lake District,Qingzhen City,Xifeng County,Kaiyang County,Xiuwen County)in the first stage,in the second stage,three villages/towns or subdistrict were selected randomly from the four districts/cities selected already,in the third stage,resident were selected randomly from two administrative villages or residential quarter that selected in the second stage.Children and elder were required to complete the investigation with the guidance of guardian.For 435 cases who were suspected AR,the Ig E in serum were determined.All subjects were divided into allergic rhinitis patients and healthy people(excluding other major diseases).According to their age,subjects were divided into four groups: children(4~18 years old),youth(18~44 years old),adult(45~59 years old)and the aged(≥ 60 years old).After that,Epidemiological data of AR patients were classified and organized,chi square test were used for single factor analysis to find possible risk factors for AR,then dichotomous Logistic regression analysis was used to find independent risk factors for AR in Guiyang.Results: In our study,1230 questionnaires were distributed while 1203 valid questionnaires were retrieved and 318 cases were diagnosed.The prevalence of AR in Qingzhen City,Yunyan,Nanming and Huaxi District of Guiyang City was 26.75%(65/243),29.61%(130/439),27.13%(105/387)and 13.43%(18/134).The prevalence of AR in Qingzhen citiy,Yunyan and Nanming district was significantly higher than that in Huaxi(X2=14.038,P=0.003<0.01),which may be related to higher urban traffic volume,population density.The prevalence of AR in Guiyang was 26.43%(318/1203),The prevalence of children was 28.96%(95/328),rank only second to the youth[29.72% (167/562)].However,in the AR guidelines,it was noted that the prevalence of children was higher,possibly related to the inclusion of children under 4 years of age.Among the 318 cases of AR patients,49 cases with a Ig E level of 100-200UL/ml,the positive rate was 15.41% and183 cases with a level of Ig E> 200UL/ml,the positive rate was 57.55%.Dust mites is the main allergens of AR patients in Guiyang,the positive rates of different age groups were 28.40% of children,31.10% of youth,26.70% of adults and 27.30% of older.In addition,the dog dander,mixed tree pollen,cockroaches,mixed mold,cashew nuts are also the more common allergens.Conclusion: 1.AR have happened in Qingzhen city,Nanming,Yunyan and Huaxi district,but the prevalence rates in the four regions is different.2.Dust mites is the main allergens of AR patients in Guiyang.3.AR patients in Guiyang are mainly concentrated on youth and children,prevalence rates of AR decreased with increasing age among those who over 45 years old.4.Genetic and environmental factors were considered to be associated with the prevalence of AR.Open the window regularly plays a important role for the prevention of allergic rhinitis. |
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