| Objective (s): Objective to investigate the effect of preoperative antibiotic use on postoperative complications, and to provide a basis for rational use of antibiotics before percutaneous nephrolithotomy.Methods:Collected in the Department of Urology of the Second Affiliated Hospital of Kunming Medical University in 189 cases of percutaneous nephrolithotomy and the clinical data of the patients, according to preoperative antibiotic use days,preoperative use of antibiotics, whether preoperative antibiotics and preoperative urine culture results were divided into corresponding groups, each group compared postoperative fever rate and the incidence of SIRS. The use of statistical knowledge that the corresponding numerical.Results:The heating rate of preoperative antibiotics 1-2 days after surgery (38.2%)and fever rate of preoperative antibiotics was 3 days after surgery (42.3%) (P = 0.615)is similar to that of preoperative antibiotics 1-2 days after surgery in patients with the incidence of SIRS (16.4%) with preoperative antibiotics over 3 days with the postoperative incidence of SIRS (19.2%) (P = 0.656) were similar, the heating rate of preoperative antibiotics 1-4 days after surgery in patients with fever (46.7%) was higher than that of preoperative antibiotics was 5 days after surgery (29.6%) (P =0.039), preoperative antibiotics 1-4 days in patients after the SIRS incidence rate(20%) higher than the preoperative application of antibiotics was 5 days after surgery in patients with the incidence of SIRS (14.8%) (P = 0.423), there was no significant difference between the rate of fever; preoperative antibiotics of the patients (40.9%)was higher than that of preoperative application of antibiotics in patients after The rate of heat (26.7%) (P = 0.142), preoperative antibiotics in patients with postoperative SIRS incidence (18.2%) was higher than that of preoperative application of antibiotics in patients with the incidence rate of SIRS (6.7%) (P = 0.193), preoperative urine culture negative patients, the heating rate of the patients with preoperative antibiotics the postoperative fever rate (35.8%) was higher than that of antibiotics before surgery in patients after surgery (25%) (P = 0.280), preoperative antibiotics in patients with postoperative SIRS incidence (11.3%) was higher than that of preoperative application of antibiotics in patients with the incidence rate of SIRS (3.6%) (P = 0.383)before operation; make use of sensitive antibiotics of postoperative fever rate (29.6%)preoperative use of non sensitive antibiotics in patients with postoperative fever rate lower than (43.2%) (P = 0.192), the use of antibiotics before surgery, the postoperative incidence of SIRS (22.2%) with preoperative use of non sensitive antibiotics in patients with postoperative SIRS The incidence (17.4%) (P = 0.753)without difference between preoperative urine culture positive patients, the rate of fever with sensitive antibiotics before operation after operation (29.6%) preoperative use of non sensitive antibiotics in patients with postoperative fever rate lower than(71.4%) (P = 0.002), the use of sensitive antibiotics before operation after operation the incidence rate of SIRS (22.2%) preoperative incidence of non sensitive antibiotics in patients with SIRS was lower than that (42.9%) (P = 0.103); preoperative urine bacterial culture positive patients with postoperative fever rate (50.9%) higher than the preoperative urine bacterial culture negative patients with postoperative fever rate(33.6%) (P = 0.026), preoperative urine bacterial culture positive patients with the incidence rate of SIRS (32.7%) is higher than the preoperative urine bacterial culture negative patients the incidence rate of SIRS (9.7%) (P = 0).Conclusion (s) : 1 the pathogenic bacteria in the urine bacteria culture of upper urinary tract calculi were the highest in Escherichia coli.2 percutaneous nephrolithotomy before the prophylactic use of antibiotics longer than 5 days of positive significance to reduce with fever and postoperative SIRS.3 for patients with moderate preoperative urinary tract bacterial cultures and urinary tract infections, the use of antibiotics without percutaneous nephrolithotomy did not significantly increase postoperative fever and the incidence of SIRS.4 the use of sensitive antibiotics before percutaneous nephrolithotomy is helpful to reduce the total postoperative fever rate, and the use of antibiotics before operation in patients with positive urine culture is significant for reducing postoperative fever and SIRS.5 there was a significant correlation between positive urine bacteria culture and postoperative fever and SIRS. Positive urine bacterial culture before percutaneous nephrolithotomy was an important risk factor for postoperative fever and SIRS... |
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