The Clinical Analysis Of Hepatolithiasis Combined With Intrahepatic Cholangiocarcinoma

Objective:by Clinical data of hepatolithiasis combined with intrahepatic cholangiocarcino-ma,analyze the clinical feature,diagnostic method and treatment effect.Method:through the electronic health records system of our hospital,patients were diagnosed hepatolithiasis from 2010-2014,30 cases of hepatolithiasis combined with intrahepatic cholangiocarcinoma and 40 cases of hepatolithiasis,divided into the observation group and the control group.Then we collect the information of those patients,including the general information,blood test,imaging data and pathological characteristics.Results:18 cases wered diagnosed hepatolithiasis combined with intrahepatic cholangio-carcinoma clearly fefore have surgery.The rates of diagnosis is 60%,8 cases wered diagnosed clearly by fast frozen pathology,4 cases wered diagnosed clearly by he postoperative pathological results.all cases of the observation group did the B-mode ultrasound examination,12 wered diagnosed clearly,The rates of diagnosis is 40%,26 cases did the CT,18 wered diagnosed clearly,The rates of diagnosis is 69.2%,21 cases did the MRI,15 wered diagnosed clearly,The rates of diagnosis 71.4%.Take the X~2 test between the rates of diagnosis of different examination,the positive rate of diagnosis of CT and MRI was not different in hepatolithiasis combined with intrahepatic cholangiocarcinoma.And the diagnosis effects of the both have advantage than the B-mode ultrasound.the CA19-9、CEA of serum in the observation group,the positive rates of detection value are86.6%、43.3% respectively,the positive rates of detection value in control group are 7.5%%、5%respectively,Take the X~2 test between two group,the differences of the positive rates of detection value CA19-9、CEA have statistical sense.18 patients underwent radical surgery,accounted for 60%,8 patients underwent palliative operation,accounted for 26.7%,the median survival time for radical surgery are 21 months,the palliative operation are 11 months.The lifetime of between which Take thettest,the result is that the lifetime of radical surgery is superior to palliative operation.Conclusion:The B-mode ultrasound examination,CT,MRI and the CA19-9、CEA of serum have significant value to the diagnosis of hepatolithiasis combined with intrahepatic cholangiocarcinoma.Founding the suspicious lesions should do fast frozen pathology to avoid missing diagnosis.The radical surgery can improve the survival rates.