Analysis On The Prescription Of Treating Age-related Macular Degeneration Based On Traditional Chinese Medicine Inheritance Platform

Objective:use the Traditional Chinese medicine inheritance support system v2.5 to preliminary explore Chinese medicine treatment medication regularity and characteristics of age-related macular degeneration,for traditional Chinese medicine treatment of age-related macular degeneration provides a new thought.Methods:in the relevant database retrieval literatures of traditional Chinese medicine treatment of age-related macular degeneration,establish new database,conduct the associativeprescription analysis,excavatethe frequency of usage of Chinese medicine treating age-related macular degeneration and the rule of the formula,then get a new prescription.Results:through the analysis of the 196 prescriptions and 168 herbs,high frequency of herbs such as poria cocos,angelica,medlar,atractylodes,salvia miltiorrhiza,licorice,astragalus,Chinese yam,Ligusticum,rehmannia glutinosa,the main drug classification are tonify deficiency drugs,promoting blood circulation to remove blood stasis drugs,the water moisture penetration,heat-cleaning drugs,hemostatic medicine.SET support for 30,confidence for 0.6,reach 34 common groups.Set correlation for 6,punishment degree for 2,excavate Core combination by three herbs constitute,add up to 23 groups.Finally conclude four Newprescriptions:(1)dangshen,dried tangerine or orange peel,atractylodes,atractylodes,dodder,wolfberry fruit,fruit of Chinese magnoliavine(2)the thistle,madder,turmeric,radix rehmanniae,field thistle,cortex moutan,(3)angelica,coix seed,rhizoma ligustici wallichii,safflower(4)white lentils,amomum villosum,lotus plumule and ginseng.Conclusion:1.Based on data mining technology such as the frequency statistics method,an improved mutual information entropy clustering method,the complex system,Unsupervised entropy clustering hierarchy,for analysis the treatment of age-related macular degeneration of prescription medication rule provides certain scientific credentials.2.The main treatment ways of age-related macular degeneration is nourish the liver and kidney,spleen,promoting blood circulation to remove blood stasis.3.The combination of core and optional new prescription by the traditional Chinese medicine inheritance support system v2.5 provides a new reference for clinical,lay theoretical foundation for the development of new drugs,but still need verification from clinical research and experimental research.