Purpose:Yidu damage of kidney theory,"not disease prevention," "disease prevention have been changed," mentor self side righting Tongluo detoxification treatment of early diabetic nephropathy of Qi stasis toxic syndrome clinical studies,observation of the effectiveness and safety of traditional Chinese medicine for the treatment of early diabetic nephropathy open up new ideas,new methods,lay the clinical foundation.Method:This study is a combination of ideological Clinical Instructor,Yidu evil doctrines and collateral disease theory,selected clinical common early diabetic nephropathy Qi stasis toxic syndrome,and clinical observation.60 cases of patients with early diabetic nephropathy will meet the inclusion criteria were randomly divided into treatment group and control group,30 in each group.Both groups were on a regular basis,the treatment group to righting detoxification Tongluo decoction for treatment,control group received losartan potassium tablets Treating,a course of 12 weeks.Observed before and after treatment clinical symptoms,reduce urinary albumin,?2-microglobulin,high-sensitivity C-reactive protein,in order to further evaluate the validity of the group side;laboratory tests were observed before and after treatment of blood,urine routine,liver and kidney function,electrocardiogram as a safety indicator to evaluate the safety of the party group.Result: The treatment group righting detoxification Tongluo soup better than the control group(P<0.05)in improving clinical symptoms,reduce urinary albumin,?2-microglobulin,discharge of high sensitivity C reactive protein and other aspects.Clinical efficacy,no side effects in clinical observation.Conclusion: Yidu damage of kidney theory as a guide prescription of righting detoxification Tongluo soup,played a protective effect on the kidneys,can be reduced microalbuminuria discharge,reduce inflammation,reduce the burden on the kidneys,delayingthe progression of diabetic nephropathy,for Chinese medicine treatment of early diabetic nephropathy and laid a solid foundation,and is worthy of clinical application. |