Value Of Pulmonary Function In Evaluation Of Stable Chronic Obstructive Pulmonary Disease

Objective:By comparing the changes of main pulmonary function indexes and the CAT scores before and after treatment in stable chronic obstructive pulmonary disease(COPD) patients in different groups, to explore the value of pulmonary function in evaluation of stable chronic obstructive pulmonary disease.Methods:Fifty-nine patients with stable COPD from November 2013 to March 2014 were gathered and divided into four groups: bronchial diastolic positive mild-to-moderate group,bronchial diastolic positive severe-to-very severe group, bronchial diastolic negative mild-to-moderate group and bronchial diastolic negative severe-to-very severe group. All patients were treated regularly one year according to the guideline for diagnosis and management of chronic obstructive pulmonary disease, then the changes of main pulmonary function indexes and CAT were compared and all data were analyzed with SPSS 17.0 software.Results:1. In bronchial diastolic positive mild-to-moderate group, FVC(3.29±0.74 L vs2.97±0.56 L), PEF(5.11±1.08 L/S vs 4.47±1.08 L/S), DLCO(6.44±2.08 mmol/min/kpa vs5.97±1.70 mmol/min/kpa) increased significantly compared with pretherapy(all P<0.05).2. In bronchial diastolic negative severe-to-very severe subgroup, IC(2.21±0.51 L vs1.99±0.55 L) and IC/TLC(44.09±10.78 % vs 39.49±7.71 %) increased significantly compared with pretherapy(all P<0.05).3. There was no significant difference about FVC, PEF, DLCO, IC, IC/TLC in bronchial diastolic positive severe-to-very severe group and bronchial diastolic negative mild-to-moderate group(all P>0.05).4. The CAT scores were obviously lower than pretherapy in four groups(all P<0.05).Conclusions:The changes of PEF and FVC can better reflect the improvement of the airflow limitation, and the changes of IC and IC/TLC can better reflect the improvement of hyperinflation.