| ObjectiveCSG is a common diseases of digestive system diseases, frequently-occ urring disease, its longer duration, easily relapse, resulting in patients with psychological and financial and material resources suffered a heavy burden, so how to improve the clinical efficacy of treatment of this dis ease is that we explore direction. Western medicine tends to lower the si mple cure, and easy to repeated, so combination of Chinese and western me dicine treatment is the focus of our exploration, and in accordance with our treatment modalities. Another With the current improvement of living standards, people living pressure, psychological factors lead to the mech anism of chronic gastritis is also exploring our direction, and emphasis o n psychological factors that can improve the efficacy and reduce the rela pse rate.This study is to observe Chaishao Liujunzi combined Deanxit treatment of chronic superficial gastritis Ganpi Buhe type clinical observation.By traditional Chinese medicine group, western medicine group and combine traditional Chinese and western medicine group are about the before and after treatment differences in clinical efficacy, to provides the reference of improving the clinical efficacy of the treatment of chronic gastritis method.MethodFirst collected and analysis chronic superficial gastritis literature, and then sort and review the system of chronic superficial gastritis of the TCM etiology and pathogenesis, syndrome differentiation, clinical treatment and Western etiology, pathogenesis, treatment. In reference to other clinical studies, based on the actual situation, to develop a more scientific research methods. This study is the randomized and controlled trial, observed from December 2014 to February 2016 period, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine clinic, aged 18-70 years diagnosed as chronic superficial gastritis patients with Ganpi Buhe. Clinical cases were collected from 81 cases meet the criteria were randomly divided into three groups, namely Western group, TCM group and combine traditional Chinese and western medicine group,27 cases each. TCM group be Chaishao Liujun Jiawei, western medicine group be Teprenone(GGA) and Deanxit, Chinese and Western medicine group were Chaishao Liujun decoction, GGA, Deanxit. Three groups before and after treatment were to fill Symptoms Lists self-rating depression scale and self-rating anxiety scale, to understand the situation before and after treatment in each group.Result1. Comparison of Integral of syndrome of TCM1.1 Comparison of the Integrative Medicine treatment group, TCM group and Western medicine group before and after 4 weeksThree groups have effect about the epigastric fullness, epigastric pain, heartburn, acidreflux, belching, nausea and vomiting, food reduction, fatigue, irritability, good sigh nine symptoms, and have a statistically significant difference(P＜0.05).1.2 Pairwise comparison among the three groups after 4 weeks of treatmentChinese and Western medicine in heartburn, reduce food satisfied, fatigue, irritability, good sigh five symptoms better effect than the traditional Chinese medicine group, western medicine.group, and significant difference was statistically significant (P＜0.05), while for epigastric fullness, epigastric pain, acid reflux, belching, nausea and vomiting symptoms three four treatment groups showed no significant difference (P>0.05). Secondly, the Medicines for fatigue, good Taixi better treatment than western medicine, the difference was statistically significant (P＜0.05). And when you have heartburn symptoms, the traditional Chinese medicine have bettet effect than western medicine, the difference was statistically significant(P＜0.05).2 Comparison of the total efficiency of TCM syndromesAfter 4 weeks of treatment,Chinese and Western medicine group, the total effective rate was 92.6%,7.4% invalid; TCM total effective rate was 85.2%, 14.8%, was invalid; Western medicine group, the total effective rate was 66.7%, 33.3% invalid; the total efficiency of the three groups by nonparametric rank sum test analysis, P＜0.01, the difference was statistically significant.3 Comparison of Anxiety and Depression Scale scoreAfter 4 weeks of treatment before and after comparison, Chinese and Western medicine group, TCM group and Western group of SAS, SDS scores decreased significantly, the difference was statistically significant(P＜0.05). After 4 weeks of treatment three pairwise comparison, the Chinese and Western medicine group of SAS, SDS have better efficacy than the traditional Chinese medicine group and western medicine group, the difference was statistically significant (P＜0.05).ConclusionChinese and Western medicine, traditional Chinese medicine and Western medicine can improve the symptoms of chronic superficial gastritis clinical symptoms(Ganpi Buhe type), but Western group in heartburn, reduce food satisfied, fatigue, irritability, best sigh effect than the TCM and Western medicine group significantly. TCM for fatigue, good Taixi better than western medicine in the treatment group. The heartburn symptoms have significantly improved compared with western medicine. In the Chinese and Western medicine group have best efficacy than the traditional Chinese medicine and Western medicine group. Reduction in anxiety and depression integral aspect, the traditional Chinese medicine and Western group best efficacy than the Western medicine group and TCM group. |
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