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Analysis Of Curative Effect Of Surgical Treatment For Laryngeal Carcinoma

Posted on:2017-02-04Degree:MasterType:Thesis
Country:ChinaCandidate:Y L WangFull Text:PDF
GTID:2284330488455201Subject:Otolaryngology science
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Objective: to analyze the laryngeal cancer clinical stage and surgical methods impact on complications and survival rate of postoperative patients with laryngeal carcinoma, methods: laryngeal carcinoma of different clinical stages of selection operation mode provides the reference method of Qinghai Province People’s Hospital in June 2011 to 2012 July ear, nose and throat(ENT) for treatment of 52 cases of laryngeal cancer patients as the research object, including 8 cases of female patients, 44 cases of male patients, age between 32 to 81 years old, the average age of the patients was 60.01 + 3.67 years, duration of 3 months to 2 years, and mean duration of patients for(1.51 + 0.26) years. Postoperative pathological examination confirmed squamous cell carcinoma. There were 2 cases of the patients with the type of the 13 patients, 37 patients with the type of the. The clinical data were analyzed retrospectively, and the clinical effect was observed according to the condition of the patients. Results: of the 52 patients, 9 patients with total laryngectomy, accounting for 17.3% of all cases; 43 patients with laryngeal resection, all cases accounted for 83.2%, which underwent vertical partial laryngectomy, 27 cases(51.92%), subtotal laryngectomy in 16 cases(30.76%). The operation is completed, this group of 52 patients, 11 patients had local complications, of which 4(45.45%) patients with pharyngeal fistula, all throat pharyngeal fistula occurred in 4 cases, no vertical laryngectomy and total laryngectomy patients, through statistical analysis, P=0.008 showed that, compared with the other two resection of laryngeal, subtotal resection after more prone to pharyngeal fistula, 2(27.27%) patients had incision infection, the throat infection occurred in 2 cases, no vertical laryngectomy and total laryngectomy patients, through statistical analysis, P=0.096, shows that the existing data are not tumor Correlation operation and postoperative infection; 2(27.27%) patients for eating cough, time total laryngectomy occurred in 2 cases, vertical laryngectomy and laryngeal resection patients did not occur in cough, through statistical analysis, P = 0.007, show that compared with the other two, throat subtotal resection more prone to cough, 4(45.45%) patients with neck in the tip of flap necrosis. The complication rate was 21.15%. Operation after the completion of all patients enrolled for a period of 3 years of follow-up, through outpatient referral of patients, access to medical history data, telephone inquiry follow-up, computer information such as account method completed follow-up. All patients were followed up for 3 years with the surgery date as the starting point. Among them, 4 patients lost contact, a total of 48 patients were alive, 1 year survival rate was 92.31%. A total of 45 patients survived 2 years after surgery, and the survival rate was 2 after 86.54% years. A total of 35 patients survived 3 years after surgery, and the survival rate was 3 in 67.31% years. Clinical stage I patients have 19 people, accounting for 36.4%, 3 years after the survival of 17 cases, 2 casesofdeath, including clinical stagePatients with 14 people, accounting for 26.3%, 10 cases survived 3 years later, death in 4 cases. The clinical staging for stage III patients have 8 people, accounting for 14.8%, 2 cases survived 3 years after death in 6 cases, which clinical stage IV patients, 11 people, accounted for 22.5%, after 3 years survival in 6 cases, 5 cases died. Through statistical analysis, P=0.009, indicating that the higher the clinical stage of tumor, the higher the mortality rate of patients. Conclusion: the total survival rate of patients with laryngeal cancer was 75.8%, 1 years, 2 years and 3 years survival rates were 95.3%, 79.8% and 72.8%, respectively. The higher the clinical stage of tumor, the more likely the patient is to pharyngeal fistula and cough, the lower the 3 year survival rate is. The second total throat surgery is easy to occur postoperative pharyngeal fistula, choking cough. The clinical stage and the choice of surgical procedure did not influence the postoperative infection rate. In response to laryngeal cancer patients in a timely diagnosis and treatment, accurate assessment of the tumor, a reasonable choice of treatment programs and promote smoking cessation.
Keywords/Search Tags:laryngeal cancer, surgical treatment, Clinical curative effect, Operation method
PDF Full Text Request
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