| Purpose:Biological morphology, impact biomechanics’ animal experiments to understand the difference of every type in bone micro-arc oxidation (micro-arc oxidation, MAO) coatings at implant with titanium osseointegration biometric interface, in order to further explore the surface of titanium implants improved technology MAO。Method:(1) Preparation of the implant:The layer of titanium implant process MAO randomized study into three experimental groups: ①use containing phosphate ions and calcium ions to the electrolyte solution of MAO treated titanium surface, the surface became titanium oxide film containing hydroxyapatite (HA) of (TiO2) Layer to group 1; ② use containing phosphate ions, calcium ions, strontium materials for the electrolytic solution with MAO treated titanium, let Sr-generating surface comprising HA/TiO2 (strontium hydroxyapatite-oxide film), set group 2. ③ first sandblasted titanium metal processing, and refreshed a side which roughness to the out side of oxide-containing with the titanium hydroxy apatite, and then used to contain phosphate ions, calcium ions of the electrolyte solution pretreated for MAO treated titanium metal, Set Group 3. While using smooth titanium implants as a control group (group D). Respectively for 1,2,3,4 all four groups were cultured for 16 implants. The implants were randomly transplanted into these twenty New Zealand rabbits bilateral femur, each side transplant four implants. Implanting was observed in the growth and after 28 days,56 days New Zealand rabbits were sacrificed to get the implant specimens, and to analyze whose biological character of the technologyResults:(A) the implant surface features:groupl of similar shape for the group 2 layer, microporous inserting-root demo surface structure similar to the distribution in a large number at crater-like, the pore diameter of 0.45～10pm, the average diameter of (5.12 ± 1.78) pm, dimensional existence through mutual. Group 3 In addition to 1, group 2 microporous structure, but also kept the pit diameter 30pm.4 surface is smooth, non-porous structure like form, there are obvious scratches the surface.(2) According to the arithmetic mean difference profile (Ra) for each group of the surface roughness:in which Ra (1)= 3.0 pm, Ra (2)= 2.6pm, Ra (3)= 4.3pm, Ra (4) = 0.2pm.(3) the surface of each experimental group dynamic contact angle:A, B groups in 2min contact angle decreased from 35 ° to 30 ° after the trial began, the contact angle is in Group C after the test 1min decreased from 20 ° to 10 ° to the end can not be measuring angles, D group compared with the contact from the start of the test has been maintained at 55 °.(4) groups of the film thickness:T (1)= 21.2pm, T (2)= 22.2pm, T (3)= 20.4pm, T (4) = 0.3pm. Compared with group 4,1 group, group 2,3 group in each group were significantly thicker film thickness (P<0.05).(5) coating each group-intensity vs. titanium substrate with:F (1)= 49.23MPa, F (2) = 48.54 MPa, F (3= 46.20 MPa.. No significant difference (P> 0.05) titanium substrate thickness-1 group, group 2,3 groups each group layer.Conclusion:(1) The use of MAO process treated with HA, Sr-HA/TiO2 oxide film of titanium implants and sandblasted Over the MAO-containing hydroxyapatite implant titanium oxide film, smooth and without electrolyte titanium implant treatment compared to its healing more and more biological properties suitable bone graft interface, help to improve the titanium ions diffusion level.(2) The use of a composite work surface blasting MAO treated rough titanium oxide film containing hydroxyapatite MAO implant treatment process than a simple application of the surface oxide film containing hydroxyapatite implants compared to its ability to integrate further strengthened the bone surface,... |
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