Analysis Of Pathological Features Of 201 Chronic Kidney Disease Cases In Xining Area Of Qinghai Province

Objective: To analysis the pathological features of 201 chronic kidney disease cases in Xining area of Qinghai Province.Method: To retrospectively summarize all the clinical-pathological date in the Affiliated Hospital of Qinghai University during 2012-2014 year.The qualitative data were presented as percentage.Fisher exact test was used to comparison among groups, a p value less than 0.05 was considered as significant.Results: 1) The most common disease was primary glomerular diseases(70.6%), followed by secondary glomerular diseases(27.8%), tubulointerstitial disease(0.4%). 2) The most common pathological type of primary glomerular disease was Ig A nephropathy(32.3%), followed by Membranous nephropathy(30.9%), Ms PGN(27.4%). The main clinical manifestations of primary golmerular disease were chronic nephritis syndrome and nephritis syndrome. The most common pathological type of secondary glomerular diseases was Henoch Schonlein purpura nephritis(33.9%), followed by Diabetic nephropathy(17.8%), hepatitis B virus associated glomerulonephritis(12.4%). 3) The chronic kidney disease occurred more common in male with male to female ratio 1.16:1, but we found no significant differences between male and female in the distribution of primary glomerular diseases pathology types(p > 0.05). The most common pathological type of secondary glomerular diseases in male was Henoch Schonlein purpura nephritis(40.6%). The most common pathological type of secondary glomerular diseases in female was lupus nephritis(25%)(p < 0.05). 4) We found no significant differences among nations in the distribution of above pathology types(p > 0.05). 5) The mean age in this study was 40.56±14.54 years. The most common pathological type of primary glomerular disease in the patients less than 45 years old was Ig A nephropathy. The most common pathological type of secondary glomerular diseases was Henoch Schonlein purpura nephritis. The most common pathological type of primary glomerular disease in the patients over than 45 years old was Membranous nephropathy. The most common pathological type of secondary glomerular diseases was Diabetic nephropathy.Conclusion : Primary glomerular disease was the most common form of Chronic kidney disease. The most common pathological type of primary glomerular disease was Ig A nephropathy, followed by Membranous nephropathy, Ms PGN. The main clinical manifestations of primary golmerular kidney disease was chronic nephritis syndrome and nephritis syndrome. The most common pathological type of secondary glomerular diseases was Henoch Schonlein purpura nephritis, followed by Diabetic nephropathy.The most common pathological type of secondary glomerular diseases in male was Henoch Schonlein purpura nephritis. The most common pathological type of secondary glomerular diseases in female was lupus nephritis. The most common pathological type of primary glomerular disease in the patients less than 45 years old was Ig A nephropathy, The most common pathological type of secondary glomerular diseases was Henoch Schonlein purpura nephritis.The most common pathological type of primary glomerular disease in the patients over than 45 years old was Membranous nephropathy. The most common pathological type of secondary glomerular diseases was Diabetic nephropathy.