| Objective:Observation of two to ShenQiDiHuang Decoction Treatment of diabetic nephropathy Ⅳ clinical curative effect of Qi and yin deficiency, blood stasis and toxin blocking col laterals. Exploration for the treatment of stage Ⅳ of TCM of diabetic nephropathy effective medicine theory and feasible method.Materials and methods:In this study, the medical records from the ward of Department of nephropathy Affiliated Hospital of Shandong University of Traditional Chinese Medicine, The 60 patients with stage Ⅳ patients with diabetic nephropathy with deficiency of both Qi and Yin, According to the order of treatment were randomly divided into experimental group and control group,30 cases in each, The control group is the only western medicine group based therapy:(1)Control of blood glucose(2)Control of blood pressure (3) education of diabetic nephropathy, a strict diet control (4) other symptomatic treatment;The test grlup:On the basis of the control grlup two to be ShenQi-DiHuang decoction, Two grlups of patients were treated for 12 weeks, Changes of lipid metabolism were observed before and after treatment, Urine protein and the changes of renal function, The changes of bolld rheology, Blood, urine, androutine, Liver function, electrocardiogrm, Record the clinical symptom score before and after treatment to compare the differences in efficacy.Results:Treatment group after treatment, The patient’s lipid metabolism, urinary protein and renal function, hemorrheology of learning, TCM clinical symptom score and so on have significantly improved than before treatment, There was significant differdece compared with control grlup. Two to ShenQi-DiHuang Decoction on blood routine test, liver function, renal function, showed no adverse effects of ecg.Conclusion:Two to ShenQiDiHuang Decoction Combined with basic treatment not only can improve the stage of diabetic nephropathy patients clinical symptoms and signs,but also can effectively regulate blood lipid, reducing urine protein, anticoagulant, anti-inflammatory. Liver function of patients no significant effects. It is one of the better method to treat diabetic ephropath-y Ⅳ, the correct use of two to ShenQiDiHuang Decoction Treatment of diabetic nephropathy IV has broad prospects. |