The Effect Of Psychosocial Factors On The Medication Compliance Of Patients With Primary Glaucoma

Glaucoma is a set of threat and damage to the optic nerve visual function relatedto the pathological elevated intraocular pressure eye disease. Medication adherence isdefined as the extent to which a patient acts in accordance with the prescribed intervaland dose of a dosing regimen. In the treatment of glaucoma, local administration ofconservative treatment in order to reduce intraocular pressure is the most commontherapy, in this circumstances, explore the factors influencing the medicationcompliance of patients with primary glaucoma is very important. Previous studiesshow that many psychological social factors may affect the patient’s medicationcompliance. On the basis of Leventhal self-regulation theory, our study introduced thepersonality traits and doctor-patient relationship variables with important influence onthe medication compliance, investigates the effect of personality traits anddoctor-patient relationship on patient illness perception, medication beliefs andmedication compliance in order to enrich and develop the self-regulation theory, andwill give a more clear, comprehensive mechanism that psychological social factorsinteraction with the medication compliance. My dissertation is divided into threeparts.1. The correlation analysis of doctor-patient relationship, personality traits,illness perception, medication beliefs and medication adherence, preliminary exploring the relationship among them.2. The Regression analysis of doctor-patient relationship, personality traits,illness perception, medication beliefs and medication compliance, preliminary exploring the mechanism of personality traits, doctor-patient relationship, illness perception, medication beliefs affect the medication compliance.3. The mediating effect of illness perception, medication beliefs between doctor-patient relationship, personality traits and medication compliance. Using structural equation modeling, build a possible interaction mechanism among various factors, analyze how the interaction between these psychological social facto rs affect patients’ medication compliance, provide the basis for clinical eye doctor to intervention.This research adopts The Morisky medication adherence scale Chinese revision, The doctor-patient relationship scale PDRQ-15, The Brief Illness Perception Questionnaire, Chinese medicine belief specific Questionnaire and EysenckPersonality Questionnaire to measure213patients with primary glaucoma, andused SPSS19.0and Lisrel8.70to analyze the data.Our study found:(1) Medication compliance significantly positively correlated to doctor-patientrelationship; and significantly negatively correlated to neurotic personality traits,specific concern medication beliefs, illness concern and illness emotional state; andpositively correlated with illness identity.(2) Extraversion/inversion, specific concern medication beliefs, doctor-patientrelationship significantly predicted the level of medication compliance.(3) The specific concern medication beliefs totally mediate the relationshipsbetween neurotic personality traits and medication compliance. The specific concernmedication beliefs totally mediate the relationships between illness perception andmedication compliance. Illness perception and specific concern medication beliefsmediate the relationship between neurotic personality traits and medicationcompliance; the doctor-patient relationship can directly predict the patient’smedication compliance, and can indirectly predict medication compliance by specificconcern medication beliefs.The results support the Leventhal self-regulation theory, enriched and developedthe self-regulation theory, give a clearer, comprehensive mechanism thatpsychological social factors interaction with the medication compliance.