Study On Syndromes Of Traditional Chinese Medicine Of Chronic Atrophic Gastritis And It’t Relationship With Images Of Gastroscope And Pathological Change

Purpose: This study aims to observe images of gastroscope and pathological change of chronic atrophic gastritis (hereinafter referred to as the CAG) patients with different TCM syndromes, explore the relationship of CAG TCM syndromes and images of gastroscope and pathological change,to provide certain microcosmic basis for differenting CAG TCM syndrome.Methods:Select128chronic atrophic gastritis patients confirmed by biopsy pathology examination,collect the patient’s general informations, TCM diagnostic informations, gastroscopy and pathological datas,differenting the TCM syndromes, and analyze the relationship of CAG TCM syndrome and images of gastroscope and pathological change by statistical methods.Results:128CAG patients are selected into this study,68cases male,60cases female, no significant differences in incidence between men and women.The age distribution is that under30years-old with low incidence,41to50years-old with higher incidence,51to60years-old with incidence increasing significantly,50years-old or above accounted for74.2%of all the cases.Most of patients have suffered from CAG for1to2years.In all clinical TCM symptoms,abdominal distension and full has the highest occurrence rate.All cases are divided into five traditional Chinese medicine syndromes according to the standard, according to the frequency from high to low in turn is: spleen and stomach deficiency>incoordination between liver and stomach> stomach Yin def iciency> Damp Heat in the Spleen and Stomach> Blood Stagnation of the Stomach. By chi-square test, there is significant statistical difference(P<0.05).Chronic atrophic gastritis common gastroscope performance according to the detection rate from high to low in turn is: white mucosa>see blood vessels through mucosa>mucosa rough>hyperplasia of particles, spleen and stomach deficiency has the highest detection rate of white mucosa, stomach Yin deficiency has the highest detection rate of see blood vessels through mucosa,both mucosa rough and hyperplasia of particles are more easily been detected in Blood Stagnation of the Stomach. By chi-square test, there is significant statistical difference (P<0.05).The distribution of Different glands atrophy degree from high to low is: mild atrophy> moderate atrophy> severe atrophy,with no significant statistical difference(P>0.05).mild atrophy has the highest detection rate in incoordination between liver and stomach, moderate atrophy has the highest detection rate in spleen and stomach deficiency, severe atrophy has the highest detection rate in stomach Yin deficiency.By chi-square test, different glands atrophy degree of TCM syndromes have significant statistical difference (P<0.05). Comparing two of them separately,mild and moderate, mild and severe, moderate and severe all have significant statistical difference (P<0.05).In128CAG patients, overall positive rate of intestinal metaplasia is53.1%mild and moderate intestinal metaplasia account for most of it, severe intestinal metaplasia account for a small number of it.With IM positive rate from high to low, syndromes in turn is: stomach Yin deficiency> Blood Stagnation of the Stomach> spleen and stomach deficiency> incoordination between liver and stomach> Damp Heat in the Spleen and Stomach,with significant statistical difference (P<0.05). Comparing two of them separately, stomach Yin deficiency and incoordination between liver and stomach,stomach Yin deficiency and Damp Heat in the Spleen and Stomach have significant statistical difference(P<0.05), other syndromes with no significant statistical difference (P>0.05).overall positive rate of Intraepithelial neoplasia is20.3%,mild Intraepithelial neoplasia account for most of it, severe Intraepithelial neoplasia account for small part of it. With Intraepithelial neoplasia positive rate from high to low, syndromes in turn is: Blood Stagnation of the Stomach> stomach Yin deficiency> spleen and stomach deficiency>Damp Heat in the Spleen and Stomach> incoordination between liver and stomach, with significant statistical difference (P<0.01). Comparing two of them separately, Blood Stagnation of the Stomach and incoordination between liver and stomach, Blood Stagnation of the Stomach and Damp Heat in the Spleen and Stomach, stomach Yin deficiency and incoordination between liver and stomach have statistical significant difference (P<0.05), other syndromes have no significant significant difference (P>0.05).Conclusions: lThe distribution of Chronic atrophic gastritis syndromes is:spleen and stomach deficiency first, incoordination between liver and stomach second, blood stagnation of the stomach least.2Spleen and stomach deficiency has the highest detection rate of white mucosa, stomach Yin deficiency has the highest detection rate of see blood vessels through mucosa, both mucosa rough and hyperplasia of particles are more easily been detected in Blood Stagnation of the Stomach.3Mild atrophy has the highest detection rate in incoordination between liver and stomach,moderate atrophy has the highest detection rate in spleen and stomach deficiency, severe atrophy has the highest detection rate in stomach Yin deficiency.4Stomach Yin deficiency type has the highest positive rate of intestinal metaplasia, blood stagnation of the stomach has the highest rate of intraepithelial neoplasia.