Clinical Analysis Of Anemia In Patients With Non-hematological Malignancies

Objectives:By retrospectively studing the cases with non-hematological malignancies,we analyse the incidence, severity,morphologic characteristics and treatment status quo of anamia in patients with non-hematologic malignant tumors, them strengthen the cognition of cancer-related anemia and the attention of the consequences of anemia.Methods:530hospitalized patients with a primary diagnosis of tumor were enrolled in this study. They who were diagnosed by pathological examination from Jan.2009to Mar.2011in the5th center hospital were investigated retrospectively. And they all have discontinued stop the radiation and chemotherapy or chemoradiation for2months or more.120normal people in phisical examinations were set as control group.The patient’s age, sex, type of tumor hemoglobin(Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell volume distribution width(RDW), folic acid, VitB12, ferritin, anemia symptoms and treatment were recorded. T test and chi-square test were used in statistical analysis with SPSS17.0software. Anemia was diagnosed when their Hb was<110g/L on admission.Results:111(20.94%)of the530patients had anemia on admission.Most of the patients were in with mild anemia. Red blood cell parameters showed that anemia of tumor patients was normal-cytic and pigment anemia, and that the more severe anemia is, the smaller erythrocyte mean corpuscular volume is. Anemia were seen in35.3%of patients with digestive system cancer,19.4%with Gynecologic cancers,18.3%with lung cancers,6.8%with urinogenital cancers, and1.8%with breast cancers. The difference of incidence of anemia in different malignancies was statistically significant (x2-44.9785, P<0.005).Grade I and II anemia accouted for15.66%; grade Ⅲ and Ⅳ5.28%.39(18.75%)of the208females were anemic compared to72(22.36%) of322male. Incidence of anemia was no significant difference between the different gender (x2=0.9948, P>0.05).1.70%of patients had anemia symptoms described in the medical record;3.02%had anemia related test;2.08%had anemia diagnosis;5.66%had the treatment for anemia;5.66%has a record of blood transfusion.No one was treated with erythropoietin.Conclusion:The incidence of anemia in patients hospitalized with tumor was high, but only few got enough medical care. Clinical workers should improve cognition in tumor patients with anemia to improve patient’s quality of life and survival by timely detection and proper treatment of anemia.