The Correlation Between Skin Barrier Function Of Soldiers Stationing In The Island And Dermatophytes

Objective: Research that whether there is correlation of skin barrierfunction and the dermatophytes infection and the influencing factors of thesoldiers stationed in the island.Methods:1.Testing skin barrier function: The three indicators to reflect theskin barrier function (transepidermal loss of water, sebum content, the stratumcorneum water content) are both measured by the multi skin tester MPA9whichis produced by Germany CK company.Test environment temperature is22℃to24℃, and the relative humidity is46%to55%. Before detection of skin barrierfunction the subjects of study get into the designated indoor room to adapt theenvironment for15minutes and wait for detection. The test regions are the faceand the groin regions, and three measurements of each quota are done in the testregions while the mean value of three measurements is given.The unit of stratumcorneum water content and Sebum content is au (arbitrary unit), and the unit oftransepidermal water loss amount is g/m2h.2. Microscopic examination: The damder from the corresponding parts ofninety three qualified subjects is scraped under aseptic condition for the fungalmicroscopic examination and culture. Microscopic examination is done by using15%KOH solution, and the culture is done by using the sand-agar medium(containing0.25%discharge glucose cycloheximide, chloramphenicol, peptone,agar medium), petri dish multipoint inoculation or double tube under25~27℃.Results: The mean value of the transepidermal water loss in the face of each group shows no statistical significance (F=0.611, P>0.05). Transepidermalwater loss amount from facial measured samples of each group has nosignificant difference from each other and has no correlation with dermatophyteinfection. The comparison of the mean value of the transepidermal water loss inthe groin of each group shows statistical significance (F=104.525, P <0.05),and the results of pairwise comparisons always make P <0.05.The comparisonsof fungus-positive group and fungus-negative group, of fungus-positive groupand the normal control group and of fungus-negative group and the normalcontrol group are with statistically significant differences. The values oftransepidermal water loss from inguinal samples of all groups are withsignificant difference, and there is a certain correlation with dermatophyteinfection.The mean value of the facial sebum conten of each group shows obviousstatistical significance (F=95.461, P<0.05), and the results of pairwisecomparisons always make P <0.05. The comparisons of fungus-positive groupand fungus-negative group, of fungus-positive group and the normal controlgroup and of fungus-negative group and the normal control group are withstatistically significant differences.The values of the facial sebum conten of allgroups are with significant difference, and there is a certain correlation withdermatophyte infection.The mean values of sebum conten from groin samples ofall groups are with no statistical significance (F=1.29, P>0.05), and there is nocorrelation with dermatophyte infection.The mean value of the stratum corneum water content of each group showsno obvious statistical significance(F=0.840, P>0.05), and there is no correlationwith dermatophyte infection. The mean values of stratum corneum water contentfrom groin samples of all groups are with no statistical significance (F=3.015, P>0.05), and there is no correlation with dermatophyte infection.The relationships of transepidermal water loss amount, sebum content, andstratum corneum water content in the samples from facial fungus-positivepositive group, fungus-negative group, and the normal control group to age,length of military service and the time on the island are with no statisticalsignificance.(P>0.05).The relationships of transepidermal water loss amount, sebum content, andstratum corneum water content in the samples from groin fungus-positive groupto age, length of military service and the time on the island are with no statisticalsignificance.(P>0.05).The relationships of transepidermal water loss amount,sebum content, and stratum corneum water content in the samples from groinfungus-negative group and the normal control group to age, length of militaryservice and the time on the island are with no statistical significance.(P>0.05).The relationship between sebum content and other factors can not be calculatedas a result of that the sebum content amount in samples from groinfungus-negative group and the normal control group is zero.Conclusions:(1)There is a certain correlation between groin transepidermalwater loss amount of the soldiers stationing in the island and infected bydermatophyte and dermatophyte infection.(2) There is a certain correlation between facial sebum conten of the soldiersstationing in the island and infected by dermatophyte and dermatophyteinfection.(3) There is no correlation between facial and groin stratum corneum watercontent of the soldiers stationing in the island and infected by dermatophyte anddermatophyte infection.(4) There is no correlation of facial and groin skin barrier function of the soldiers stationing in the island and infected by dermatophyte, age, length ofmilitary service and the time on the island.