| Tibetan medicine Banga and Bangna are Tibetan conventional herbs.Due to a number of reasons,there are large regional differences in the origin,medicinal parts and clinical applications of Banga and Bangna in different regions of the Tibetan areas. Quality standards is not perfect, it is difficult to ensure the clinical drug specifications, safety and quality and the drug production control, while not conducive to the regulation of the pharmaceutical market. In view of this situation, our group carry out research on the historical changes, the current usage situation and resources of Tibetan medicine Banga and Bangna,and evaluate on the medicinal rationality of the different original species. The results are summarized as follows:(1) using the methods of literature analysis, carrying out the herbal medicine research on Tibetan medicine Banga and Bangna,we find that the main origin of Tibetan medicine Banga are Aconitum naviculare Stapf and A.tanguticum (Maxim) Stapf,the main origin of Tibetan medicine Bangna are A. flavum Hand.-Mazz., A.pendulum Busch and A. Kongboense Lauener multiple medicinal plants of Aconitum L. The ancient and modern records of the functions and indications of Bangga are basically the same, and expansion,but Bangna is more complicated. Tibetan docters use them respectively because of large differences between them.(2)Taking resources survey on the main territories of the Tibetan medicine Banga and Bangna, including Tibet, Gansu, Qinghai and Sichuan.and taking production, usage survey with Tibetan medical institutions,Tibetan pharmaceutical companies and herb markets of the region of the four provinces as the object of the research. The results showed that:the currently actual origin of Tibetan medicine Bangga are Aconilum naviculare Stapf and A.tangulicum (Maxim) Stapf.,we find that A langulicum (Maxim) Stapf is mainly distributed in Sichuan Province (Heishui County,Hongyuan County,Jinchuan County,Maerkang County), Gansu Province (Tianzhu County), Qinghai Province (Xunhua County, Huzhu County, Guide County, Guinan County, Tongde County, Maqin County, Yushu Prefecture, Nangqian County), Tibet (Changdu area) and so on, A. naviculare Stapf is mainly distributed in Tibet(County Mozhugongka,Cona County,Forest County,Shannan Prefecture, gongbo’gyamda,Chayu, Longzi County); the mainstream commodity of Tibetan medicine Bangna mainly come from A. flavum Hand.-Mazz., A.pendulum Busch and A. Kongboense Lauener.,but there are confusion origin. The original plat of Bangna A.pendulum Busch is mainly distributed in Gansu(Tianzhu County),Qinghai(Huangyuan,Guide County,Maqin County,Yushu County), Tibet (Basu County, Sog County), A. flavum Hand.-Mazz. is mainly distributed in Gansu Province(Xiahe County,Tianzhu County), Qinghai(Xunhua County,Huzhu County, County,Maqin, Tongde County, Maduo), Tibet(Mozhugongka County,Baqing,Dingqing County,Chaya County,Naidong) etc.A kongboense Lauener is distributed in Tibet (Gongbo’gyamda, LInzhou County, Damxung County).By the field survey,we grasp the distribution of part of the origin plant, the resource endowments situation and the usage in both the clinical practice and the pharmacology of Tibetan medicine Banga and Bangna.(3) Carrying out the comparative analysis of the chemical compositions and similarity which on five species of Tibetan medicine Banga and Bangna by HPLC method, combined with Chinese medicine fingerprint software and SPSS cluster analysis, The results showed that:the components of Aconitum naviculare Stapf and A.tanguticum (Maxim) Stapf has a certain similarity,which suggesting that it is reasonable to be as the same origin plant; the components of A. pendulum and A. flavum both are similar, but be large different with A. Kongboense Lauener.,which show that the origin are quite different,it is required to further study its medicinal mechanism. Sample components are quite different between Bangga and Bangna, which shows that it is reasonable to separate the two applicationsThis study provide a scientific basis for further standardize,improving its quality standards, standardized clinical and production medication and the rationality of medicinal research. |