The Clinical Study Of Treating Premenstrual Syndrome (PMS) With The Decoction Of Zi-Shen-Jie-Yu

Objective: This research is aimed at observing the clinical effect of kidney emptyliver constraint type premenstrual syndrome through tonifying kidney and relievingdepression soup, and discusses the mechanism of action combining reproductionendocrine hormone, catecholamine neurotransmitters, so that we can find somemethod and medicine to treat this disease.Method:Put66patients into2grouprandomly,34for treatment group, treat them at taking tonifying kidney and relievingdepression soup orally;32for control group, treat them at taking sapor peripateticismpill orally.Observe2groups of cases on clinical symptoms and sign change methodsfor before and after treatment, also test the endocrine hormone (E2, P, PRL),catecholamine neurotransmitters (NE、5-HT、β-EP) indicators change for themseparately.Result:There is endocrine and nerve functional disturbance in kidneyempty liver constraint type premenstrual syndrome patients. After treatment, totaleffective rate for treatment group and control group are:88.24%and68.75%. There issignificant difference for curative effect (P<0.05). In alleviating clinical symptomsand signs, adjusting endocrine and vegetative nerve functional, treatment group isbetter than control group (P<0.05).Conclusion: Tonifying kidney and relievingdepression soup has good curative effect at treating kidney empty liver constraint typepremenstrual syndrome. It can improve corpus luteum function through correcting theendocrine disorder and adjusting vegetative nerve function. It can also ease thepremenstrual dysphoria and irritability, alleviate breast tenderness and abdominal pain, relieve dizzy and headachy, lighten insomnia and dreamful sleep.It is effective methodto treat kidney empty stomach type premenstrual syndrome.