Clinical Research On Treating Lung Excess And Kidney Deficiency In Mild Case Of Infantile Asthma Through Purging Lungs, Tonifying Kidney Dissolving Phlegm And Relieving Asthma

Objective: This research is intended to systematically investigate, theoretically andclinically, treating lung excess and kidney deficiency in acute infantile asthma throughpurging lungs, tonifying kidney, dissolving phlegm and relieving asthma, and also toanalyze its mechanism of function.Methodology: Divide80infantile patients infected with acute asthma equally intotreatment group and comparison group at random and treat them respectively. Patients inthe comparison group are prescribed low-absorption and medium-dosage glucocorticoid（budesonide0.5-1mg/time） and/or shrot-term-effect β: receptor stimulant （terbutaline2.5-5mg/time）; Patients in the treatment group are treated purging lungs, tonifying kidney,dissolving phlegm and relieving asthma with traditional Chinese herbal medicines.Observe the general conditions of the two groups and major symptoms, including cough,panting, and shortness of breath and chest distress; observe in the laboratory quantitativechanges of EOS, levels of IgA、IgG、IgM in blood serum and also amounts of CD3and CD8before and after the treatment. Seven days makes a treating and observing period. Recordchanges of physical characteristics before and after the treatment, esp. on the third and fifthdays of treating period. Observe and compare between the two groups in terms of changesof lung function and pulmonary peak expiratory flow before and after the treatment.Result: Clinical research shows that the total effective rate of the treatment group is95%and87.5%for the comparison group with former obviously better than the latter（P＜0.05）, which is reflected in relieving major symptoms such as panting, coughing, throatphlegm rale, shortness of breath, chest distress and wheezing rale （P＜0.05）. Treatmentsfor the two groups show no difference in relieving nasal flapping, three depressions sign, mental disorder and urinal disorder（P＜0.05）. There are differences in relieving lungfunction and peak flow, with the treatment group better than the comparison on（eP＜0.05）.There are no differences in relieving abnormal white blood cell counting （P＞0.05）. Theeffective rate is related to the age, state and course of illness （P＜0.05）: the lower in age,the better the effect and vice versa; the less serious the illness, the better effect and viceversa; the longer the course of illness, the better the effect and vice versa. The researchfinding of clinical safety index shows: Treatment through purging lungs, tonifying kidney,dissolving phlegm and relieving asthma has no side effects on major organs.Conclusion: Treating lung excess and kidney deficiency in acute infantile asthmathrough purging lungs, tonifying kidney, dissolving phlegm and relieving asthma is safeand effective, and it is worthwhile to be advocated and applied to clinical treatment.