The Clinical Research Of Tongqiao Huatan Dingxuan Decoction On Vertebral-basilar Artery Insufficiency Vertigo

Objective:Discussion of Tongqiao Huatan Dingxuan Decoction on vertebral-basilar artery insufficiency vertigo (blood stasis and phlegm type)efficacy and explore its mechanism of actionMethods:put the patients that meet the inclusion criteria of84cases of vertebral-basilar artery insufficiency vertigo (blood stasis and phlegm type patients.) into two groops. Group therapy clinical give Tongqiao Huatan Dingxuan decoction, daily use of an agent, decoct soup juice400ml, divided into two lukewarm take, take200ml, plus oral and aspirin tablets100mg/time,1times/D; the control group with Changchun West Dean injection20mg/D+250ml saline infusion, oral worship of aspirin tablets100mg/time,1times/D; the course of treatment was2weeks. Two groups of control of blood pressure, blood lipid, blood sugar medicine applications are the same. Before treatment on two groups of gender, age, course of disease, clinical integration, underlying diseases and general data were compared by statistical treatment, no significant difference (P>0.05), comparable to. After treatment based on clinical evaluation, blood rheology, blood lipid, blood glucose and safety observation of changes for assessment. Results:1. Comparison of curative effect of two groups:The treatment group12cases were cured,15cases, effective in10cases, ineffective in5cases, the total effective rate was88.10%; the control group7cases were cured,14cases, effective in11cases, ineffective in10cases, the total effective rate was78.57%. By Ridit test, P<0.01, illustrate the curative effect in treatment group was better than the control group.2. the influence to blood glucose and blood lipid:The treatment group after treatment than before treatment of lipids is improved, significantly higher than the control group, with significant difference (P<0.05). Application of removing blood stasis and phlegm drug treatment group with blood lipid regulating effect.3. The influence to Blood rheology:After the treatment, the treatment group in the whole blood viscosity improvement than the control group (P<0.05), the treatment group of Tongqiao Huatan Dingxuan decoction used in traditional Chinese medicine improve the microcirculation, reducing blood viscosity, prevent thrombosis and cerebral arteriosclerosis in the rat4. the observation of safety:Before and after treatment in two groups of three routine, liver function, electrocardiogram and other major indexes (see table six), before and after treatment in two groups of main index were not significantly add to the damage, the x2test, before and after treatment in two groups have no significant difference.Conclusion:Tongqiao Huatan Dingxuan decoction could obviously improve the syndrome of traditional Chinese medicine, regulating blood fat, lower blood viscosity, improve microcirculation, clinical use of more security, to close all phlegm vertigo (vertebral-basilar artery insufficiency vertigo) has better therapeutic effects...