The Contrast Of Two Schemes For Treating Keloid With Combined Therapy

AIM: To discuss the clinical effect of keloid treatment with surgerycombining β-rays and to compare the advantage and disadvantage of thetwo schemes.METHODS: The patients were randomly divided two groups (teamA and B), and submitted radiotherapy following excision in short and longcourses respectively. The total irradiation dose was1500～1800cGy. Allpatients were followed up more than18months. The hardness of the healedwounds and neighboring normal skin was measured using scar sclerometerpreoperation and the1st、6thand18thmonth postoperation.RESULTS: From2005to2008, the long course irradiation group Aincluded46patients and the short course irradiation group B50patients.In the tenth month, the total effect rates of two groups were90.9%and90.2%respectively. There was no significant difference in the two groups.In the eighteenth month, the total effect rates of team A and B were89.9%and69.2%. The efficiency of team A was superior to team B. Thescar hardness examinations showed that the scar hardness of the keloid skin was significantly greater than that of the neighboring normal skin(P＜0.01). After12months of the treatment, the hardness of the healedwounds was significantly reduced with time.CONCLUSION: Surgery combining β-rays is a efficacious way fortreating keloid. Within one year, there was no significant difference of therecurrence rate in the two groups. The short course irradiation scheme is aconvenient method because it can shorten the time of radiotherapy.However,the recurrence rate increased in the later stage. This methodshould be improved in detail.