The Clinical Research Of ZiShenQingXin Decoction Treating Perimenopausal Syndrome Caused By Fire Excess From Yin Deficiency

Purpose:Objectiving the Clinical research of ZiShenQingXin decoction treating perimenopausal period syndrome caused by fire excess from Yin deficiency and exploring its mechanism provides the basis for the treatment of perimenopausal period syndrome caused by fire excess from Yin deficiency permit clinical application.Method:Clinical design methods that meet the inclusion criteria,30cases of patients with climacteric syndrome wang card income group, using their own before and after contrast. four weeks of a course of treatment,2consecutive treatment; the main symptoms observed in patients with medication before and after the, serum E2, FSH, modified Kupperman perimenopausal symptoms rating scale integration (KMI), the change of the Pittsburgh Sleep Quality index (PSQI).Result:(1) After treatment, clinical total effective rate of86.67%, suggesting that the pure in heart the ney soup can ease the patient’s clinical symptoms;(2)The main symptoms points:The main symptoms before and after treatment, the points difference was statistically significant (P <0.05), indicating the Qingxin ney soup hot flashes, sweating decline in the number of attacks.(3)The modified Kupperman symptom score:Kupperman points difference before and after treatment was statistically significant (P<0.05), indicating that the pure in heart ney soup can effectively relieve the symptoms of the climacteric syndrome patients.(4) hormone levels: After treatment, E2levels showed an-upward trend, FSH levels are declining, the results of statistically non-significant (P>0.05), suggesting that a pure heart the ney soup had no significant effect on the hormonal changes;(5) Pittsburgh Sleep Quality Index points fell in the Pittsburgh Sleep Quality Index (PSQI):before and after treatment (P<0.05), statistically significant, suggesting that the pure in heart ney relief decoction on sleep.(6) The safety analysis:30patients after treatment, no significant adverse reactions. Blood routine, urine routine, liver and kidney function, ECG, breast B ultrasound, gynecological B ultrasonic and cervical liquid-based examination no obvious abnormalities, suggesting that drug clinical application of good security.Conclusion:Qingxin ney soup can cfleetively alleviate the the wang permit the clinical symptoms of the menopause syndrome, such as hot flashes, sweating, insomnia. etc., and does not affect the blood level of estradiol, the hormone therapy other a more acceptable treatment method fails or refuses to hormone therapy in menopausal syndrome patients to provide safe and effective treatment.