Comparative Study Of The Conflict Monitoring Functions In Children With And Without ADHD

Part one Family environment and Behavioral study ofdifferent subtypes of attention deficit hyperactivitydisorder in childrenObjective:To investigate the risk factors which indicate behavior problems anddegree of conflict function defects in different subtypes of attention deficit hyperactivitydisorder (ADHD)，this study compared behavioral problems, family environment andconflict function in children with and without ADHD.Methods:87children with ADHDand38matched controls performed Simon-Stroop task while questionnaires (ParentSymptom Questionnaire and Family environment Scale)were acquired from theirparents.Results:Questionnaire indicated that children with ADHD-combined(ADHD-C)had the highest score of conduct problem,learning problem,hyperactivity-impulsion andhyperactivity index than ADHD-I and matched controls in PSQ. ADHD-I and ADHD-Chad higher score of contradiction and lower score of family cohesion,emotionalexpression,knowledge and entertainment than matched controls in FES-CV.Behavior dataindicates that the correct rate of children with ADHD-I and ADHD-C inSimon-incongruent trials(Siin:0.76±0.13,0.69±0.13) and Stroop-inconsistent trials(Stin:0.82±0.10,0.78±0.08)were lower and reaction time of children with ADHD-I andADHD-C in the Siin(876.4±97.34ms,893.8±130.1ms)and Stin(864.4±91.82ms,860.2±125.0ms)were longer than matched controls (Siin：0.81±0.11,810.4±136.1ms；Stin：0.87±0.08,797.4±136.1ms). Pearson Correlation analysis suggests that some factots in the FES-CV hadcorrelation with behavioral problems.Conclusion:This finding indicates that Poor family environment is the risk factor that indicate behavioral problems in children with ADHDand behavioral problems，conflict function defect of ADHD-C are more serious thanADHD-I and matched controls.Part two An Event-Related Potentials and behavior Study forConflict monitoring in Attention Deficit Hyperactivity DisorderChildrenObjective:We analyze the differences of ERP and behavior results when school agechildren with Attention-deficit/hyperactivity disorder (ADHD) and normal controlsin wereperforming the spatial Simon-Stroop task,to investigate whether children with ADHDexistence dysfunction of conflict monitoring, seek the changes and significance in differentleads of ERP components. Methods:112children with ADHD and101matched controlsperformed Simon-Stroop task. Results:Behavior result: Performance showed the ADHDhad more error and slower reaction time compared to controls in the Siin and Stin.Event-related potentials (ERP): N1and P2components: amplitude and latency in the Fz,Fcz,Cz lead compared with the normal group, the difference was statistically significant,but there is no condition main effect; N2a and N2b components: amplitude and latency inFz, Fcz lead compared with the healthy controls, the difference was statistically significant,while the presence of condition main effects; P3components: amplitude and latency in Cz,Pz lead, compared with normal group, the difference was statistically significant, while thepresence of condition main effect.Conclusion: The data of the study most likely reflectedthat there was impaired conflict monitoring processing in children with ADHD. The wholecognitive process, ERP is not only abnormal in the early stages,but also in the late stages.Components of ERP represent a different meaning in the varied leads and stand for specialsignificance.