Clinical Study Of Niaotongkakenaiqi Tablets In Lower Urinary Tract Infection

Objective:To evaluate the efficacy and safety of Niaotongkakenaiqi tablets in treating the low urinary tract infection(Stranguria syndrome-Damp-heat in lower-JIAO).Method:According to the rules of random, double-blinding, double-imitating and controlled experiment with positive medicine, we selected 76 cases conforming to low urinary tract infection from traditional hospital of Hubei at Department of Nephrology since December 2009 to February 2011. They were randomly divided into test group(which had 56 cases) and control group (which had 20 cases). In test group, they were given Niaotongkakenaiqi tablets, four tablets each time, two times each day, before meals, and sanjin mimetic, three tablets each time, three times each day, before meals; while in control group, they were given sanjin tablets, three tablets each time, three times each day, before meals, and Niaotongkakenaiqi mimetic, four tablets each time, two times each day, before meals. After seven days, the scores of TCM syndromes and laboratory index were observed Results:1. After seven days'treatment, the cure rates on lower urinary tract infection efficacy of test group and control group were 22.05%,21.88%, the improvement rates were 62.41%,60.62%, the total improvement rates were 84.46%,82.50%, there is no statistically difference between two groups (P>0.05).2. After seven days'treatment, the clinical cure rates on Chinese symptom efficacy of test group and control group were 25.00%,24.64%, the effective rates were 46.43%,44.57%, the markedly effective rate were 71.43%,69.21%, the total effective rates were 87.50%,86.64%, there is no statistically difference between two groups (P>0.05).3. After seven days'treatment, the test group and control group in terms of TCM symptoms and signs were improved integration, the difference between group comparison, the differences were statistically significant (P<0.01); Comparing the differences between the groups, the differences can be that was not significant (P>0.05).4. After seven days'treatment, the test group and control group in the urine, the two groups before and after treatment of urinary white blood cells compared were significantly different (P <0.01); the two groups there was no significant difference between (P> 0.05); the two groups before and after treatment of urinary red blood cells compared were significantly different (P<0.01); the two groups there was no significant difference between (P>0.05).5. After seven days'treatment, the experimental treatment group and control group bacteria in the urine bacteria examination of negative rate, the two groups before and after treatment of urine bacteria examination negative rate, which negative bacteria examination of urine after treatment were 60.71% and 58.33%, the difference was no significant difference (P>0.05).6. No obviously adverse effect was found in the clinical test.Conclusion:Niaotongkakenaiqi tablets can improve obviously the syndromes and laboratory index of patients with low urinary tract infection (Stranguria syndrome-Damp-heat in lower-JIAO). Niaotongkakenaiqi tablet is one of the efficacy and safety medicines for treating low urinary tract infection (Stranguria syndrome-Damp-heat in lower-JIAO).