Clinical Evaluation Research On The Curative Effect Of Fufangbaqiayin On The Impaired Glucose Tolerance With Damp-Heat Type

ObjectiveObserved the curative effect of Fufangbaqiayin on the impaired glucose tolerance patients with damp-heat type in order to provide clinical evidence about clinical appli-cation of Fufangbaqiayin and the development of the new drug about Fufangbaqiayin. Methods84 cases impaired glucose tolerance patients were selected in the research and were divided into two groups randomly,41 cases were selected as the experimental group and treated by lifeway intervence and traditional Chinese medicine "Fufangbaqiayin";43 cases were selected as the control group and treated by lifeway intervence and Glucobay, Each group was cured for two months. Observed the changes of fasting blood-glucose (FPG),2 hour blood sugar in OGTT test (2hPG), fasting insulin (FINS), HbA1C,insulin resistance index (HOMA—IR) and clinical symptoms before and after curing in the two groups.Results1.The changes of observation index:(1) Compared with before treatment, the FPG,2hPG,FINS,HbA1C,HOMA-IR in the two groups after treatment were reduced. The differences were highly significant (P<0.01);(2) The differences of FPG,2hPG,FINS,HbA1C, HOMA-IR between experimental group and control group after treatment were not significant (P>0.05);(3) Compared with before treatment, the marks of TCM clinical symptoms in the experimental group and control group after treatment were reduced. The differences of the marks of TCM clinical symptoms after treatment in the two group were highly significant (P<0.01);(4) After treatment comparing the experimental group with control group,the diff-erences of the marks of TCM clinical symptoms were highly significant (P<0.01); The differences of the D-value of the marks of TCM clinical symptoms before and after treatment in the two group were highly significant (P<0.01);The melioration of the marks of TCM clinical symptoms in the experimental group was higher than that in the control group. 2.The evaluation of security:Five cases of patients in the control group weren't windy and didn't defecate abnormally originally, occurring windy and defecating frequently in three weeks after taking the medicine.But the symptoms were alleviated after keeping on taking the medicine. The experimental group didn't appear side-effects.ConclusionsFufangbaqiayin could reduce blood sugar and fasting insulin effectively, improve insulin resistance index and traditional Chinese medicine clinical symptoms.There were no side-effects through preliminary observation. Fufangbaqiayin had not significant difference from Glucobay in reducing blood sugar,but it was better than Glucobay in improving patients'clinical symptoms.It was an effective prescription in curing impaired glucose tolerance patients with damp-heat type.