| Objective:To investigate the effects of Guizhencao atomization in treatment of dry eye.Methods:52 patients were selected from outpatients of Chinese Medicine Hospital Eye Center in Jiangsu Province from July 2010 to April 2011. The investigation was divided into three groups: Distilled water group (12 cases), Guizhencao NO.1 group (20 cases),and Guizhencao NO.2 group (20 cases). Patients of each groups had been treated. Data was collected for corneal staining, tear film break-up time, tear flow, dry eye,corneal sensation and the patients'main symptoms were observed. Pre-treatment and post-treatment in each group were compared respectively. Post-treatment information in three groups were analysed.Results: Results were compared after four weeks from the last treatment for each groups. Their post-treatment data with their original result were also compared. The results for corneal staining, tear flow, corneal sensation,and dry eye was not significant improved for Distilled water group. But the results for tear film break-up time, tear flow, and the clinical symptoms of dry eye was significant improved (P<0.05). The results for corneal staining, tear flow, corneal sensation, break-up time, tear flow, and the clinical symptoms of dry eye was significant improved (P<0.05) for Guizhencao NO.1 group. And the results for corneal staining, tear flow, corneal sensation, break-up time, tear flow, and the clinical symptoms of dry eye was significant improved (P<0.05) for Guizhencao NO.2 group. Both Guizhencao NO.1 group and Guizhencao NO.2 group have their significant impact in different aspect.Conclusion:Topical administration of Chinese medicine by atomization is feasible; Guizhencao atomizer is effective in treatment of dry eye, and also related to the concentration of the fogging agent. |
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