The Preliminary Study Of TCM Intervention To Non-cardiogenic Myocardial Injury In ICU Patients

Object:Research on the TCM intervention to patients in ICU medical intervention in critically ill with non-cardiac myocardial injury incidence of acute left ventricular failureMethod:using Prospective, Completely randomized Methods. Strict inclusion and exclusion criteria will be based on ICU stay consistent with non-cardiac patients with myocardial injury in critically ill patients with symptoms of complete collection and Syndromes Scale.Yang deficiency in which patients meet the Chinese as the research object,The distribution of the envelope under a hospital order,Respective groups of patients for the envelope group.The pilot phase of a total of 22 patients were found in Chinese medicine yang deficiency in early intervention into clinical trials of treatment,1 case of them not yet reached the experimental period due to transfer out of ICU, Therefore, this experimental study period a total of 21 patients, 14 patients in the experimental group(shen-fu injection and Conventional treatment group),Control group,7 cases(Conventional treatment group).Detection of changes in vital signs,complete daily observation of acute heart failure table,according to the progress of clinical trials testingThe Concentration of Troponin T(cTnT),APACHEⅡscore, ECQNon-invasive cardiac function tests relevant results(CI, CO, ACI, SVR, TRC),Ejection Fraction (EF)and The TCM symptom scale.Analysis and compare the above data,to compare the different of the two groups of patients of the incidence of acute left heart failure.Result:(1)There are 2 patients occur acute left heart failure in experimental group,the incidence of acute left heart failure is 14.3%.The control group,There are 4 patients occur acute left heart failure in the control group,the incidence of acute left heart failure is 57.1%,two groups have obvious difference (P<0.05).(2)The differentiation factor measurement of the two groups before the experimental is490.57±81.345,482±93.957.After experimental the dates change to 454.071±86. 578,479.286±93.136, there are no differences between the two groups(P>0.05),so do the patients in the control group,however,in the experimental group,the dates have obvious differences(P<0.05).(3)Before the experimental,some dates of experimental group:cTnT(0.205±0.063) ng/ml,CI(2.936±0.496)L/min/m2,CO(4.557±0.750)L/min,ACI(98.143±8.085)/100s2,S VR(1330.214±210.179)dyn×sec×cm-5, TRC(51.214±5.899)/kohm, EF%(43.286±4.304), APACHEⅡsore(16.786±2.045);After the experimental, the dates:cTnT(0.138±0.062) ng/ml, CI(3.336±0.439)L/min/m2, CO(5.278±0.545)L/min, ACI(120.429±8.045)/100s2, SVR(1205.929±90.524)dyn×sec×cm-5,TRC(46.357±3.973)/kohm, EF%(45.357±4.1622), APACHEⅡsore(14.357±1.646).Where the CI,CO, ACI, TRC, EF%, cTnT and APACHEⅡsore have differences(P<0.05).Conclusions:Shen-fu injection can reduce the incidence of acute left heart failure,which the patients in critically ill with non-cardiac myocardial and Differentiation is a yang deficiency in ICU medical intervention;Comparison of the experimental group,shen-fu injection can Improve cardiac function in patients with myocardial injury,manifast as Enhanced myocardial contractility, Increase cardiac output.Prmopt TCM intervention to non-cardiogenic myocardial injury in ICU patients has Important clinical value.