Spleen And Kidney Related Theories In Chinese Medicine Diabetes Medical Records Application Data Mining Research

This article uses the tradition fundamental research and the modern data mining methods to the Chinese medicine spleen-kidney correlation theory, the XiaoKeBing spleen-kidney correlation theory, as well as its in famous TCM doctors' XiaoKeBing medical notes' application these three aspects has conducted systematic research.The Chinese medicine spleen-kidney correlation theory initiates from the"Huang Di Nei Jing"and"Nan Jing"in the pre-Qin times. Han Zhang Zhongjing has been in clinical development of the doctrine of succession. After the Sui and Tang dynasties, different schools of thought begin to explore the relationship between the spleen and kidney, there has been scholarly contention. Sun Simiao proposes that"does not invigorate the kidney, if makes up the spleen"viewpoint.Southern Song dynasty Xu Shuwei advocates that"makes up the spleen not, if invigorates the kidney"viewpoint. Jin and Yuan dynasties four big tcm doctors think spleen and kidney are related to each other. In Ming dynasty, most influential appeared has made up the school of thought warm, emphasizing warming spleen and kidney. And Li Zhongzi proposes"the kidney explicitly for the congenital foundation, spleen foundation of the day after birth", symbolizes the spleen-kidney correlation theory established. The Qing dynasty doctors' understanding is supplement and consummation in the predecessor foundation. To the modern times, Professor Deng Tietao proposes"the five internal organs related"theory. As the theory of five internal organs related important part of,Chinese medicine spleen-kidney correlation theory attractes wide attention, causes this theory tend to be mature. The contemporary doctors take the spleen kidney correlation theory generally, apply to many diseases, which XiaoKeBing is one of.XiaoKeBing in Chinese medicine, including diabetes, is one of clinical upper common illnesses and frequently occurring diseases. At present its disease incidence rate assumes the daily trend of escalation, and it has many compli- cations, already has become one of serious illnesses threatening human being' healthy following coronary heart disease and cancer, has aroused the domestic and foreign medical arena universal interest. As early as more than 2000 years ago,"NeiJing"from the theory of spleen-kidney correlation has put forward to the name of XiaoKe, This is the earliest record on XiaoKe in the Chinese medical literature. Eastern Han dynasty Zhang Zhongjing stresses that XiaoKe' disease bit is in the XiaJiao, having corrected the shortcoming of"NeiJing"which elaborated the XiaoKe' disease bit in the ZhongJiao and ShangJiao , for ShenXiao proposed that builds the foundation. In Sui and Tang dynasties, the understanding of the connotation of XiaoKe is more clearly. Sui Dynasty Zhen Liyan not only put forward to a more complete and accurate concept of XiaoKeBing, but also divided broad sense XiaoKe into XiaoKeBing,XiaoZhongBing,XiaoShenBing three types, and XiaoZhongBing, XiaoShenBing'disease positions are separately located on the spleen, stomach and kidney, has further been clear about the spleen, stomach, and kidney's importance in XiaoKebing. In Jin and Yuan times doctors discuss XiaoKeBing to be deeper, Propose the ShangXiao, ZhongXiao, and XiaXiao's name explicitly,And ZhongXiao is attributable to the stomach, the XiaXiao is attributable to the kidney. After Ming and Qing dynasties, XiaoKebing's under- standing continues to develop. Ming dynasty Zhang Jingyue proposes the YangXiao and YinXiao's concept for the first time. Pointed out that YinXiao is attribu- table to the kidney and nourish of kidney should be the principle. Ming dynasty Dai Sigong proposes XiaoPi for the first time .Particular emphasises on the spleen in the pathogenesis of XiaoKeBing. Ancient times the doctors embark from the spleen-kidney correlation theory XiaoKeBing morbidity factor conclusion is : Insufficiency of the spleen is the initiating factor for XiaoKeBing's morbidity; Deficiency of the kidney is the key factor; Deficiency of the spleen and kidney is the main pathogenesis of XiaoKeBing .Throughout the ages documented XiaoKe Bing treatment prescription, we can find out that: more than 20 prescriptions were used to adjust spleen and kidney , such as JinGuiShenQiWan,LiuWeiDiHuang Wan,JiShengShenQiWan,ZhiBaiShenQiWan,BaiHuTang,BaiHuJiaRenShenTang,SanHuang Tang,YuNvJian,TiaoWeiChengQiTang,QiWeiBaiZhuSan, etc. Therefore, embarking from the spleen-kidney correlation theory to discusse XiaoKeBing's treatment is the ancient and modern numerous medicines common choice.In order to objectively verify the spleen-kidneyrelated theory in guiding the treatment of XiaoKeBing and its medication rules. In this paper, on the basis of research on the spleen-kidney related and the XiaoKeBing spleen-kidney related theory, We have used frequency analysis and cluster analysis data mining techniques, carried on the earnest analysis of mining to 139 pieces of XiaoKeBing medical notes of 47 famous TCM doctors. Discovered that in XiaoKeBing's location of disease, five internal organs have involve in, but the kidney, stomach, spleen are of the greater frequency. And the main return of spleen, stomach and kidney 37 high frequency Chinese herbs such as TianHuaFen,ShengDiHuang,ShanYao,MaiDong,ZhiMu,ShuDiHuang,XuanShen,ShiGao,FuLin, etc. Has confirmed the Chinese medicine spleen-kidney correlation theory instructing function, then have carried on the symptoms and the medicine cluster analysis to under the spleen- kidney correlation theory instruction's 82 example medical notes, excavated 9 pieces of clustering symptoms combinations, divides into the kidney yang deficiency syndrome; spleen yang deficiency syndrome; kidney yin deficiency syndrome; spleen qi deficiency with both Yang and blood deficiency, blood stasis damp spleen; wei huo flourishing card; QiYinLiangXu 7 pieces of syndromes; And 9 pieces of cluster medicine combinations. After analysis,they are similar to LiZhongTang, XiaoKePingPian, ShengMaiYin, DangGuiBuXueTang, PingWeiSan, ErChenTang, BuHuanJinZhengQiSan, JinGuiShenQiWan, ZiBaiDiHuangWan, MaiWeiDi HuangWan, LiuWeiDiHuangWan ,BaiHuTang, TiaoWeiChengQiTang, HuangLianJieDuTang, SanHuangTang and other prescriptions. Have revealed spleen-kidney relevance theory's scientific connotation and directive function in treating in XiaoKe Bing from objective angle. The syndromes and medication rules are the present famous TCM doctors' academic experiences, can be used in clinical practice. As to this theory in the application of ancient doctors' XiaoKeBing medical records needs to be further studied.