IGA Nephropathy Study On Correlation Between TCM Syndromes And Clinical Factors

IgA nephrosis (immunoglobin A nephropathy) is the disease incidencerate highest primary kidney glomerulus disease, also our country's mostcommon primary kidney glomerulus diseases,occupies the primary kidneyglomerulus disease of 30%-40%.It is one of end last-stage renal failuremost common reasons in our country, share 20%～40% of all dialysispatients around.In recent years, Chinese medicine scholars from thedifferent angles to IgA nephrosis cause of disease pathogenesis, weredoing classification dividing and the treatment researches etc, hascarried on the massive beneficial explorations, and obtained many successresearches. This research collected 2002～2006 the IgA nephrosis patients,adopt the multi-central investigation method, has developed IgA nephrosisChinese medicine sign and the clinical examination, kidney pathologyrelations etc as a clinical factor relevant research, IgA nephrosisChinese medicine sign diagnosis standardization provides basis,instruction treatment, and prognosis.This article divides into two parts, the first part for the theoricalresearch part, divided into two summaries, "IgA Nephrosis Chinesemedicine Pharmacy Research Progresses" to IgA nephrosis cause of diseasepathogenesis, diagnosis and treatment, cooperation of Chinese and Westernmedicine treatment, Chinese medicine diagnosis classification and thekidney pathology relations, experimental study factors etc, in the nearten years of Chinese medicine research summarizing the outline. "IgANephrosis Modern Medical research Progresses" to IgA nephrosisepidemiology, pathogenesis, pathology, treatment, prognosis aspects etc,has concluded a summary for modern medicine researches.Second part is a clinical research part. This research goal conductsthe research to IgA nephrosis Chinese medicine diagnosis classificationwith the clinical various factors of relevance, conveniently make aprognosis of patient's condition, in relevance to clinical treatment.Reviews of 202 examples clinical case of illness, "Chinese medicine NewMedicine Treatment of Chronic Nephritis Clinical Research GuidingPrinciple of Chinese medicine sign diagnosis standard carries ondiagnosis classification in 2002", root-deficient sign divided into theSpleen-kidney Yang-Deficiency, Liver-kidney Yin-deficiency, Qi andYin-deficiency, Lung-kidney Qi-Deficiency four classifications, tiprepletion sign divided into damp-heat,damp-turbidity, blood stasis,external contraction four classifications. Observed all the above varioussigns and sex, clinical manifestation, laboratory check labels, pathologyparameter, pathology standard relations. The result showed in 202examples patients with root-deficiency sign, Qi and Yin-deficiency weremost seen, while tip repletion sign, heat-damp sign were most seen, whileclinical classification with unusually non-symptoms urine examinationare most seen. Spleen-kidney Yang-Deficiency, Liver-kidneyYin-deficiency, Qi and Yin-deficiency, Lung-kidney Qi-Deficiency four kind of signs comparisons, Spleen-kidney Yang-Deficiency patients age ofillness were quite old, the higher the symptoms total score, the higherdiastolic pressure is; 24 hours urine proteins quota, Triglycerides,creatinine level is higher than other root-deficiency signs.Manifestation of nephrosis synthesis syndrome/Massive Proteinuriapatients are most seen. The bigger Lee pathology classification, kidneypellet total score, acorn tube total score, chronic index, activity indexare higher than other signs. In tip-repletion sign classification,damp-turbidity sign proves 24 hours urines proteins quota, cholesterol,creatinine level is higher than other root-deficiency signs. The biggerLee pathology classification, acorn tube total score, active index arehigher. The blood stasis sign in the pellet total score, blood vessel totalscore is higher.The research indicated in IgA nephrosis, the sickness nature isroot-deficiency and tip-repletion sign, root-deficiency sign were Qi andYin-deficiency, and tip-repletion sign were mainly damp-heat sign. Inthis root-deficiency sign, the spleen-kidney Yang-Deficiency, theroot-deficiency sign spleen-kidney Yang-deficiency and thedamp-turbidity sign, the prognosis is not good. In tip-repletion sign,blood stasis sign in symptom total score is quite high,the age of illnessare quite high, course of an illness is longer, pellet total score andblood vessel total score are higher, the treatment are more difficult.According to above conclusions, analyse and descript the condition ofillness and prognosis, it has a significant meaning in the clinicaltreatment.