Bupiyichang Decoction Lies Between Purely To The Uc Model Mouse Blood The Element-8 Level Influence Research

[Aim]:In order to explain the effect of BPYCT, we investigated the effect of it on treating experimental UC in mice.We also study the connection between IL-8 and UC to explain the effect of the recipe.[Methods]:We devide 100 mice into 5teams, including normal, model, high Chinese herb, low Chinese herb and SASP.Give mice DSS to make UC models and observe the weight, stool and hiden blood of mice.Choose the colon-tissue of mice to evaluate the damage-level.At last, measure the IL-8 amount of blood and analyse what can the recipe do to IL-8.[Results]:After therapy, IL-6 level decreases.The pathologic changes of colon mucosa and symptoms are both improved.This experiment shows that BPYCT is effective to DSS models.This recipe can improve the symptoms.The mechanism may be related to inhibiting inflammatory factors (IL-8).