| Objective:To study the therapeutical effect of the decoction of Zishenhangan on peripheral menopause syndrome(PMS), and to explore its action mechanism. Methods: Weselected 60 patients with PMS, observe the clinical symptoms' improvement after treatmentand detect the concentrition of E2,FSH,LH,β-EP,IL-2,LPO,BGP,CT,PTH in the blood. Results:The clinical symptoms are significantly improved and the clinical total efficiency is 98.33%.The improvement of Kupperman scores is very significant (P<0.01). After treatment, the concentrition of FSH, LH in the blood is lowered, while the concentrition of E2 in the blood is raised (P<0.05). The concentrition ofβ-EP,IL-2,LPO,BGP,CT,PTH is significantly evaluated after treatment (P<0.05). Conclusions:Zishenhanganon peri-menopausal period of liver syndrome has good therapeutic effect, can effectively alleviate hot flushes and sweating, dizziness, tinnitus, insomnia and other menopause symptoms, its role is to correct the disorder from the whole of the endocrine and autonomic disorders to improve the imbalance of bone metabolism, is a comprehensive treatment of menopause certificate valid prescriptions. |