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Clinical Application Of Nasal Resistance And Nasal Reflex Nasal Measurement In Allergic Rhinitis

Posted on:2017-05-05Degree:MasterType:Thesis
Country:ChinaCandidate:J WuFull Text:PDF
GTID:2174330482984579Subject:Traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
ObjectiveCompare the difference of rhinomanometry and acoustic rhinometry datas between allergic rhinitis patients, healthy adults and patients with allergic rhinitis, and the data of nasal cavity before and after Chinese medicine treatment, to provide a basis for clinical research.Methods76 patients from otolaryngology are regarded as the research object, among them, healthy people group is 24 cases, allergic rhinitis group is 26 cases, non-allergic rhinitis group is 26 cases. Then their nasal airway resistance and acoustic rhinometry data are measured and analyzed statistically.20 allergic rhinitis patients are treated with Chinese medicine AnMinFang for 2 weeks. Before and after the treatment, subjective symptom scores, nasal resistance and acoustic rhinometry are recorded and analyzed.Results1 Comparison of measurement data of nasal resistance in three groups, there is no significant difference between the groups in the nasal resistance with the inhale and exhale of the left and right nostril (P> 0.05); the nasal resistance in the inhale of the left side, exhale of the left side, inhale of the right side, and the left and right nasal resistance are no significant difference between the healthy group and allergic rhinitis, allergic rhinitis and non allergic rhinitis group (P> 0.05),the data of healthy group is smaller than non allergic rhinitis group and there is a significant difference (P< 0.05); the exhale of the right side in nasal resistance between the three groups are significantly different (P< 0.05), and the healthy group is minimum, maximum is non allergic rhinitis; nasal inspiratory resistance, expiratory nasal resistance, unilateral nasal resistance and bilateral total nasal resistance between allergic rhinitis and non allergic rhinitis group are no significant difference(P> 0.05), and the nasal resistance data in the allergic rhinitis group is greater than that in the healthy group (P< 0.05).2 On the three groups of nasal acoustic rhinometry data using t test, among the three groups, MCA1, MD1 and MD2 data are no statistically significant differences(P> 0.05); MCA2, NMCA, unilateral NCV and bilateral total NCV in allergic rhinitis group and non allergic rhinitis group are no significant differences(P> 0.05), while the data in allergic rhinitis group is less than that in healthy groups (P< 0.05).3 Before and after the treatment of AnMinFang, bilateral total nasal resistance value, unilateral nasal resistance value, NCMA and NCV data are no significant statistical differences(P> 0.05). nasal congestion, nasal itching, rhinorrhea, sneezing, these four groups of main symptom improvement in SRS and VAS are statistically significant differences(P< 0.05), and nasal itching is improved obviously. The total score of symptoms and signs after treatment is significantly different than that before treatment(P< 0.05), and the total effective rate is 55%.Conclusion1 Nasal mucosa inflammation may lead to nasal obstruction symptoms and abnormal change of objective indicators of nasal resistance and acoustic rhinometry data, and there is no obvious difference in allergic rhinitis group and non allergic rhinitis group. And rhinomanometry and acoustic rhinometry have been used as parts of auxiliary examination of the nasal diseases,and we need to expand the sample size to explore the range of normal value of the objective index of nasal cavity.2 Before and after the treatment of AnMinFang, the objective data of nasal airway resistance and acoustic rhinometry are no significant statistical differences. It is not the same as the subjective symptoms scores. This phenomenon may be related to a variety of factors, and it need to be discussed.3 Before and after the treatment of AnMinFang, the four main symptoms, nasal congestion, nasal itching, rhinorrhea, sneezing, are improved. The symptom scores point out that TCM AnMinFang treat allergic rhinitis has certain clinical application value. To guide the clinical treatment, the curative effect evaluation should refer to the overall subjective symptoms score and the objective data of rhinomanometry and acoustic rhinometry.
Keywords/Search Tags:TCM AnMinFang, Acoustic Rhinometry, Rhinomanometry, Allergic Rhinitis
PDF Full Text Request
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